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根据 AAPM TG-218 报告,对新型螺旋断层放疗平台进行临床个体化治疗前质量保证的分析。

Analysis of clinical patient-specific pre-treatment quality assurance with the new helical tomotherapy platform, following the AAPM TG-218 report.

机构信息

Medical Physics Department, Veneto Institute of Oncology IOV-IRCCS, Via Gattamelata 64, 35128, Padova, Italy.

Dipartimento di Fisica e Astronomia 'G. Galilei', Università degli Studi di Padova, Padova, Italy.

出版信息

Radiat Oncol. 2021 Nov 22;16(1):226. doi: 10.1186/s13014-021-01952-w.

Abstract

PURPOSE

This study presents patient-specific quality assurance (QA) results from the first 395 clinical cases for the new helical TomoTherapy® platform (Radixact) coupled with dedicated Precision TPS.

METHODS

The passing rate of the Gamma Index (GP%) of 395 helical QA of patient-specific tomotherapy, acquired with ArcCHECK, is presented, analysed and correlated to various parameters of the plan. Following TG-218 recommendations, the clinic specific action limit (AL) and tolerance limit (TL) were calculated for our clinic and monitored during the analysed period.

RESULTS

The mean values ​​(± 1 standard deviation) of GP% (3%/2 mm) (both global and local normalization) are: 97.6% and 90.9%, respectively. The proposed AL and TL, after a period of two years' process monitoring are 89.4% and 91.1% respectively.

CONCLUSIONS

The phantom measurements closely match the planned dose distributions, demonstrating that the calculation accuracy of the new Precision TPS and the delivery accuracy of the Radixact unit are adequate, with respect to international guidelines and reports. Furthermore, a first correlation with the planning parameters was made. Action and tolerance limits have been set for the new Radixact Linac.

摘要

目的

本研究展示了新的螺旋 TomoTherapy® 平台(Radixact)与专用的 Precision TPS 结合的前 395 例临床病例的个体化质量保证(QA)结果。

方法

通过 ArcCHECK 获得的 395 例个体化 Tomotherapy 螺旋 QA 的伽玛指数(GP%)通过率进行了分析,并与计划的各种参数进行了相关性分析。根据 TG-218 建议,为我们的临床制定了特定的临床可接受标准(AL)和耐受标准(TL),并在分析期间进行监测。

结果

GP%(3%/2 mm)(全局和局部归一化平均值)的平均值(± 1 个标准差)分别为 97.6%和 90.9%。经过两年的过程监测,建议的 AL 和 TL 分别为 89.4%和 91.1%。

结论

体模测量与计划剂量分布非常吻合,表明新的 Precision TPS 的计算准确性和 Radixact 单元的输送准确性符合国际指南和报告的要求。此外,还对规划参数进行了首次相关性分析。为新的 Radixact 直线加速器设置了行动和耐受标准。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/773e/8607724/85219b712f29/13014_2021_1952_Fig1_HTML.jpg

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