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评估 AAPM-TG-218 建议:使用 SunCHECK 对 IMRT 和 VMAT 质量保证进行 Gamma 指数容限和行动限评估。

Evaluating AAPM-TG-218 recommendations: Gamma index tolerance and action limits in IMRT and VMAT quality assurance using SunCHECK.

机构信息

Department of Radiation Oncology, Shaanxi Provincial Tumor Hospital, Xian, Shaanxi, China.

School of Nuclear Science and Technology, Xi'an Jiaotong University, Xi'an, Shaanxi, China.

出版信息

J Appl Clin Med Phys. 2024 Jun;25(6):e14277. doi: 10.1002/acm2.14277. Epub 2024 Jan 19.

Abstract

PURPOSE

This study aimed to improve the safety and accuracy of radiotherapy by establishing tolerance (TL) and action (AL) limits for the gamma index in patient-specific quality assurance (PSQA) for intensity-modulated radiation therapy (IMRT) and volumetric-modulated arc therapy (VMAT) using SunCHECK software, as per AAPM TG-218 report recommendations.

METHODS

The study included 125 patients divided into six groups by treatment regions (H&N, thoracic and pelvic) and techniques (VMAT, IMRT). SunCHECK was used to calculate the gamma passing rate (%GP) and dose error (%DE) for each patient, for the planning target volume and organs at risk (OARs). The TL and AL were then determined for each group according to TG-218 recommendations. We conducted a comprehensive analysis to compare %DE among different groups and examined the relationship between %GP and %DE.

RESULTS

The TL and AL of all groups were more stringent than the common standard as defined by the TG218 report. The TL and AL values of the groups differed significantly, and the values for the thoracic groups were lower for both VMAT and IMRT. The %DE of the parameters D, D, and D in the planning target volume, and D and D in OARs were significantly different. The dose deviation of VMAT was larger than IMRT, especially in the thoracic group. A %GP and %DE correlation analysis showed a strong correlation for the planning target volume, but a weak correlation for the OARs. Additionally, a significant correlation existed between %GP of SunCHECK and Delta4.

CONCLUSION

The study established TL and AL values tailored to various anatomical regions and treatment techniques at our institution. Establishing PSQA workflows for VMAT and IMRT offers valuable clinical insights and guidance. We also suggest developing a standard combining clinically relevant metrics with %GP to evaluate PSQA results comprehensively.

摘要

目的

本研究旨在根据 AAPM TG-218 报告建议,通过为强度调制放射治疗 (IMRT) 和容积调制弧形治疗 (VMAT) 使用 SunCHECK 软件为患者特定质量保证 (PSQA) 建立伽马指数的耐受 (TL) 和行动 (AL) 限值,提高放射治疗的安全性和准确性。

方法

该研究纳入了 125 名患者,根据治疗区域(头颈部、胸部和盆腔)和技术(VMAT、IMRT)分为六组。使用 SunCHECK 计算每个患者的计划靶区和危及器官 (OARs) 的伽马通过率 (%GP) 和剂量误差 (%DE)。然后根据 TG-218 建议为每个组确定 TL 和 AL。我们进行了全面分析,比较了不同组之间的 %DE,并研究了 %GP 与 %DE 之间的关系。

结果

所有组的 TL 和 AL 均比 TG218 报告中定义的通用标准更严格。各组的 TL 和 AL 值差异显著,VMAT 和 IMRT 的胸组值均较低。计划靶区的参数 D、D、D 和 OARs 的 D、D 的 %DE 差异有统计学意义。VMAT 的剂量偏差大于 IMRT,尤其是在胸组。%GP 和 %DE 相关性分析显示计划靶区具有很强的相关性,而 OARs 相关性较弱。此外,SunCHECK 的 %GP 与 Delta4 之间存在显著相关性。

结论

本研究在本机构建立了适用于各种解剖区域和治疗技术的 TL 和 AL 值。为 VMAT 和 IMRT 建立 PSQA 工作流程提供了有价值的临床见解和指导。我们还建议开发一种将临床相关指标与 %GP 相结合的标准,以全面评估 PSQA 结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/89f3/11163510/044959305397/ACM2-25-e14277-g002.jpg

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