The Post Graduate and Research Department of Chemistry, Mar Thoma College, Mahatma Gandhi University, Tiruvalla, 689103, Kerala, India.
The Post Graduate Department of Mathematics, St. Gregorios College, University of Kerala, Kottarakara, 691531, Kerala, India.
Mikrochim Acta. 2021 Nov 22;188(12):424. doi: 10.1007/s00604-021-05066-8.
The presence of excess L-amino acid in the Murchison meteorite, circular polarization effect in the genesis of stars and existence of chirality in interstellar molecules contribute to the origin of life on earth. Chiral-sensitive techniques have been employed to untangle the secret of the symmetries of the universe, designing of effective secure drugs and investigation of chiral biomolecules. The relationship between light and chiral molecules was employed to probe and explore such molecules using spectroscopy techniques. The mutual interaction between electromagnetic spectrum and chirality of matter give rise to distinct optical response, which advances vital information contents in chiroptical spectroscopy. Chiral plasmonic gold nanoparticle exhibits distinctive circular dichroism peaks in broad wavelength range thereby crossing the limits of its characterization. The emergence of strong optical activity of gold nanosystem is related to its high polarizability, resulting in plasmonic and excitonic effects on incident photons. Inspired by the development of advanced chiral plasmonic nanomaterials and exploring its properties, this review gives an overview of various chiral gold nanostructures and the mechanism behind its chiroptical properties. Finally, we highlight the application of different chiral gold nanomaterials in the field of catalysis and medical applications with special emphasis to biosensing and biodetection.
默奇森陨石中存在过量的 L-氨基酸、恒星形成中的圆偏振效应以及星际分子中的手性存在，这些都有助于地球上生命的起源。手性敏感技术已被用于揭示宇宙对称性的秘密，设计有效的安全药物以及研究手性生物分子。光与手性分子之间的关系被用于使用光谱技术探测和研究这些分子。电磁光谱与物质手性之间的相互作用产生了独特的光学响应，在手性光谱学中增加了重要的信息含量。手性等离子体金纳米粒子在较宽的波长范围内表现出独特的圆二色性峰，从而突破了其特征的限制。金纳米系统强光学活性的出现与其高极化率有关，从而对入射光子产生等离子体和激子效应。受先进手性等离子体纳米材料发展及其性质的启发，本综述概述了各种手性金纳米结构及其手性性质背后的机制。最后，我们强调了不同手性金纳米材料在手性催化和医学应用领域的应用，特别强调了生物传感和生物检测。
