[Clinical evaluation of ofloxacin against complicated urinary tract infections].

Clinical efficacy of ofloxacin (OFLX) against complicated urinary tract infections was examined in 20 patients. OFLX was administrated orally at a dose of 200 mg, three times (daily 600 mg) for 14 to 102 days. The overall clinical efficacy was rated excellent in 8 cases (40%), moderate in 7 cases (35%) and poor in 5 cases (25%) with a total efficacy of 75%. Bacteriological efficacy, 17 out of 24 strains (70.8%) isolated were eradicated after OFLX administration. The strains that appeared after OFLX treatment were P. cepacia and Candida sp. No severe side effects were found in these patients.