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2019 冠状病毒病对 HIV 感染者的影响。

The impact of coronavirus disease 2019 on people with HIV.

机构信息

División de control de VIH, ITS, Hepatitis virales y Tuberculosis. Ministry of Health, Madrid, Spain.

AIDS Research Network. Ciber de Enfermedades Infecciosas. Institute of Health Carlos III Madrid, Spain.

出版信息

Curr Opin Infect Dis. 2022 Feb 1;35(1):9-14. doi: 10.1097/QCO.0000000000000799.

Abstract

PURPOSE OF REVIEW

The COVID-19 pandemic materialized in 2020, the year the international community had expected to meet the interim targets to end AIDS by 2030. Forty years into the HIV pandemic, the COVID-19 pandemic challenges the achievements made in HIV and may even reverse some of them.

RECENT FINDINGS

This article provides an overview of the impact of COVID-19 on people with, and at risk of, HIV infection. It addresses where the global response to HIV was expected to be by 2020, analyzes the impact of COVID-19 on HIV-related outcomes and reviews the impact of HIV on COVID-19 related outcomes.

SUMMARY

The COVID-19 pandemic has had a profound impact on the response to HIV infection through disruption of prevention, testing, and access to antiretroviral treatment, as well as on the management of long-term HIV and mental health. This negative impact has been unequal throughout the world and across populations and deepens inequities in health. HIV does not increase Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) susceptibility once confounders are taken into account and inconsistencies are reported regarding its direct role on clinical severity. In post-COVID-19 scenarios, new models for HIV testing and care are likely to be consolidated. Monitoring responses needs high-quality epidemiological data and collaborative research.

摘要

目的综述

2020 年,全球迎来了有望实现 2030 年终结艾滋病目标的中期时间节点,而新冠疫情却突然暴发。在艾滋病毒流行 40 年后,新冠疫情对艾滋病防治工作带来了前所未有的挑战,甚至可能导致一些防治成果付诸东流。

最新发现

本文概述了新冠疫情对艾滋病毒感染者和高危人群的影响。文中首先介绍了 2020 年全球艾滋病防治工作的预期进展,分析了新冠疫情对艾滋病相关结局的影响,并回顾了艾滋病毒对新冠疫情相关结局的影响。

总结

新冠疫情严重扰乱了艾滋病预防、检测和抗病毒治疗工作,对长期艾滋病和精神健康管理也带来了严重影响,从而对艾滋病防治工作产生了深远影响。这种负面影响在全球范围内和不同人群中是不平等的,加剧了健康方面的不平等。从混杂因素方面考虑,艾滋病毒并不会增加严重急性呼吸综合征冠状病毒 2(SARS-CoV-2)的易感性,并且关于其对临床严重程度的直接作用存在不一致的报告。在后新冠疫情时代,很可能会建立新的艾滋病毒检测和治疗模式。监测应对措施需要高质量的流行病学数据和协作研究。

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