School of Exercise and Nutritional Sciences, San Diego State University, San Diego, California, USA.
J Med Food. 2022 Apr;25(4):381-388. doi: 10.1089/jmf.2021.0063. Epub 2021 Nov 23.
Mangos are an understudied fruit rich in fiber and polyphenols that have been linked to better metabolic outcomes and promotion of satiety. The purpose of this study was to examine the effect of mango consumption on postprandial glucose, insulin, and satiety responses. Using a randomized crossover study design, 23 overweight and obese men and women consumed 100 kcal snacks of fresh mangos or isocaloric low-fat cookies on two separate occasions. Insulin and satiety hormones were measured at baseline and 45 min post-snack consumption. Glucose was measured at baseline, 30, 60, 90, and 120 min after snack consumption. Satiety questionnaires were completed at baseline and every 20 min for 120 min post-consumption. Both mangos and low-fat cookies increased insulin, with a significantly lower increase for mangos compared with low-fat cookies at 45 min post-snack consumption ( ≤ .05). Glucose increased at 30 min for both snacks; however, the increase was significantly higher for low-fat cookie consumption ( ≤ .05). Cholecystokinin increased after mangos and low-fat cookie consumption ( ≤ .05); however, no differences were detected between the snacks. Adiponectin increased after mango consumption ( ≤ .05) but not after low-fat cookies. Mango consumption reduced hunger, anticipated food consumption and thirst, and increased feelings of fullness ( ≤ .05). Low-fat cookie consumption increased fullness for a shorter time period and did not reduce participants' desire to eat. These results suggest that relative to a refined cookie snack, mangos promote greater satiety and improve postprandial glycemic responses. Future research on long-term effects of mango consumption on food intake, weight control, and glucose homeostasis is warranted. Clinical Trial Registration number: #NCT03957928.
芒果是一种研究较少的水果，富含纤维和多酚，这些物质与更好的代谢结果和促进饱腹感有关。本研究旨在研究芒果消费对餐后血糖、胰岛素和饱腹感反应的影响。采用随机交叉研究设计，23 名超重和肥胖的男性和女性在两次不同的时间分别食用 100 卡路里的新鲜芒果或等热量的低脂曲奇饼干作为零食。在基线和零食摄入后 45 分钟测量胰岛素和饱腹感激素。在基线、30 分钟、60 分钟、90 分钟和 120 分钟后测量血糖。在基线、零食摄入后每 20 分钟和 120 分钟后完成饱腹感问卷。芒果和低脂饼干都能增加胰岛素，与低脂饼干相比，芒果在零食摄入后 45 分钟时胰岛素增加明显较低（≤.05）。两种零食在 30 分钟时血糖都升高；然而，低脂饼干的血糖升高幅度明显更高（≤.05）。胆囊收缩素在食用芒果和低脂饼干后增加（≤.05）；然而，在零食之间没有发现差异。在食用芒果后，脂联素增加（≤.05），但在食用低脂饼干后没有增加。芒果消费减少了饥饿感、预期食物消费和口渴感，并增加了饱腹感（≤.05）。低脂饼干消费在较短的时间内增加饱腹感，并且不会减少参与者的进食欲望。这些结果表明，与精制饼干零食相比，芒果能促进更强的饱腹感，并改善餐后血糖反应。需要进一步研究芒果消费对食物摄入、体重控制和葡萄糖稳态的长期影响。临床试验注册号：#NCT03957928。
