Mian Abrar, Pachorek Mark, Sam Andre-Philippe, Ruel Nora H, Yang David, Kohler Tobias S, Warner Jonathan N
Midwestern University, Long Grove, IL.
Pasadena City College, Pasadena, CA.
Urology. 2022 Feb;160:182-186. doi: 10.1016/j.urology.2021.11.008. Epub 2021 Nov 20.
To investigate which preoperative findings portend poor improvement in storage symptoms in patients undergoing plasma kinetic enucleation of prostate (PKEP).
A single surgeon series of patients who had undergone PKEP with minimum 1 year follow up were evaluated. Patients were grouped into those with less than 33% improvement in storage symptoms (LIS) according to the international prostate symptom score (IPSS) and those with greater than 33% improvement in storage symptoms (GIS). Pre and postoperative factors were evaluated, along with IPSS, storage symptoms percentage (the total from frequency, urgency and nocturia divided by the total IPSS), bother index, and post void residual (PVR) at 6 weeks, 4 months, and yearly.
Two hundred sixty-eight patients had a minimum 1 year of follow up and had completed the IPSS. IPSS and bother index improved significantly from preoperatively to all time points post operatively in both groups, but the difference was greater in the GIS group. Patients in the GIS group had significantly larger prostates, more prostatic ingrowth, higher preoperative PVR, and a higher overall IPSS compared to the LIS group. Those in the LIS group had a higher incidence of prior prostate surgery, and a higher BMI. However, storage symptom percentages were equal between the GIS and LIS groups at all time points.
Greater prostatic ingrowth, larger prostate volume, higher preoperative PVR volume, and a higher overall IPSS was associated with greater improvement in storage symptoms. Prior prostate surgery and higher BMI portend less improvement in storage symptoms.
探讨哪些术前检查结果预示着接受等离子体动力学前列腺剜除术(PKEP)的患者储尿期症状改善不佳。
对由单一外科医生实施PKEP且随访至少1年的患者系列进行评估。根据国际前列腺症状评分(IPSS),将患者分为储尿期症状改善低于33%(LIS)的患者和储尿期症状改善高于33%(GIS)的患者。评估术前和术后因素,以及6周、4个月和每年时的IPSS、储尿期症状百分比(尿频、尿急和夜尿症的总和除以IPSS总分)、困扰指数和残余尿量(PVR)。
268例患者至少随访了1年并完成了IPSS评估。两组患者从术前到术后所有时间点的IPSS和困扰指数均显著改善,但GIS组的改善差异更大。与LIS组相比,GIS组患者的前列腺明显更大、前列腺向内生长更多、术前PVR更高且总体IPSS更高。LIS组患者既往前列腺手术的发生率更高,BMI也更高。然而,GIS组和LIS组在所有时间点的储尿期症状百分比均相等。
前列腺向内生长更多、前列腺体积更大、术前PVR体积更高以及总体IPSS更高与储尿期症状改善更大相关。既往前列腺手术和更高的BMI预示着储尿期症状改善较少。