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经尿道 1470nm 二极管激光汽化术与等离子体前列腺剜除术治疗良性前列腺增生的回顾性研究。

Transurethral 1470 nm diode laser vaporization versus plasma kinetic enucleation of the prostate for the treatment of benign prostatic hyperplasia: A retrospective study.

机构信息

Department of Urology, Affiliated Xiaoshan Hospital, Hangzhou Normal University, Hangzhou, Zhejiang, China.

Department of Urology, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.

出版信息

Medicine (Baltimore). 2023 Aug 25;102(34):e35031. doi: 10.1097/MD.0000000000035031.

Abstract

To compare the efficacy, safety, and complications of transurethral 1470 nm diode laser vaporization and plasma kinetic enucleation of prostate (PKEP) in benign prostatic hyperplasia treatment. A retrospective matched-paired comparison of patients treated using transurethral 1470 nm diode laser vaporization (n = 40) or PKEP (n = 40) was conducted. Baseline characteristics, preoperative data, and postoperative outcomes at the 24-month follow-up of the patients were recorded. The present study found no significant preoperative differences between the 2 treatment groups. Compared with PKEP, 1470 nm diode laser vaporization had a significantly shorter operation time and less intraoperative blood loss, but there were no marked differences between the 2 groups in terms of postoperative bladder irrigation time, catheterization time, and hospital stay. Moreover, at the 24-month follow-up postoperatively, there were no marked differences in the International Prostatic Symptomatic Score (IPSS), quality of life (QOL), maximum urinary flow rate (Qmax), and post-void residual urine volume (PVR) between the 2 groups. IPSS, QOL, Qmax, and PVR had improved significantly compared to preoperative assessment at 24-month follow-up in both groups and there was no significant difference in the variation of IPSS, QOL, Qmax and PVR before and after the operation. Furthermore, complications were comparable between the 2 treatment groups. Transurethral 1470 nm diode laser vaporization and PKEP are effective strategies in the treatment of benign prostatic hyperplasia. However, 1470 nm diode laser vaporization offers advantages over PKEP in terms of shortening operation time and reducing intraoperative bleeding. Nonetheless, further research with a larger number of patients and long-term follow-up is necessary to confirm and validate these findings.

摘要

比较经尿道 1470nm 二极管激光汽化术和前列腺等离子动力学剜除术(PKEP)治疗良性前列腺增生的疗效、安全性和并发症。对经尿道 1470nm 二极管激光汽化术(n=40)或 PKEP(n=40)治疗的患者进行回顾性配对比较。记录患者的基线特征、术前数据和术后 24 个月的随访结果。本研究发现两组患者术前无显著差异。与 PKEP 相比,1470nm 二极管激光汽化术的手术时间明显缩短,术中出血量明显减少,但两组患者术后膀胱冲洗时间、导尿时间和住院时间无明显差异。此外,术后 24 个月随访时,两组患者的国际前列腺症状评分(IPSS)、生活质量(QOL)、最大尿流率(Qmax)和残余尿量(PVR)均无明显差异。两组患者的 IPSS、QOL、Qmax 和 PVR 均较术前有明显改善,术后 IPSS、QOL、Qmax 和 PVR 的变化与术前无明显差异。此外,两组患者的并发症相当。经尿道 1470nm 二极管激光汽化术和 PKEP 是治疗良性前列腺增生的有效方法。然而,1470nm 二极管激光汽化术在缩短手术时间和减少术中出血方面优于 PKEP。然而,需要进一步研究更多的患者和长期随访,以证实和验证这些发现。

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