Department of Psychiatry, Jeonbuk National University Medical School, 20, Geonji-ro, Jeonju, 54907, Republic of Korea.
Research Institute of Clinical Medicine of Jeonbuk National University-Biomedical Research Institute of Jeonbuk National University Hospital, Jeonju, 54907, Republic of Korea.
Sci Rep. 2021 Nov 23;11(1):22749. doi: 10.1038/s41598-021-01574-y.
Childhood trauma (ChT) is a risk factor for psychosis. Negative lifestyle factors such as rumination, negative schemas, and poor diet and exercise are common in psychosis. The present study aimed to perform a network analysis of interactions between ChT and negative lifestyle in patients and controls. We used data of patients with early-stage psychosis (n = 500) and healthy controls (n = 202). Networks were constructed using 12 nodes from five scales: the Brief Core Schema Scale (BCSS), Brooding Scale (BS), Dietary Habits Questionnaire, Physical Activity Rating, and Early Trauma Inventory Self Report-Short Form (ETI). Graph metrics were calculated. The nodes with the highest predictability and expected influence in both patients and controls were cognitive and emotional components of the BS and emotional abuse of the ETI. The emotional abuse was a mediator in the shortest pathway connecting the ETI and negative lifestyle for both groups. The negative others and negative self of the BCSS mediated emotional abuse to other BCSS or BS for patients and controls, respectively. Our findings suggest that rumination and emotional abuse were central symptoms in both groups and that negative others and negative self played important mediating roles for patients and controls, respectively.Trial Registration: ClinicalTrials.gov identifier: CUH201411002.
儿童期创伤 (ChT) 是精神病的一个风险因素。反刍、消极图式、不良饮食和缺乏锻炼等负面生活方式因素在精神病中很常见。本研究旨在对患者和对照组中 ChT 与负面生活方式之间的相互作用进行网络分析。我们使用了早期精神病患者（n=500）和健康对照组（n=202）的数据。使用来自五个量表的 12 个节点构建网络：简要核心图式量表 (BCSS)、沉思量表 (BS)、饮食习惯问卷、体育活动评分和早期创伤清单自我报告简短版 (ETI)。计算了图的度量。BS 的认知和情感成分以及 ETI 的情绪虐待是患者和对照组中节点可预测性和预期影响最高的节点。对于两组来说，情绪虐待是连接 ETI 和负面生活方式的最短路径中的一个中介。BCSS 的负面他人和消极自我分别介导 ETI 对其他 BCSS 或 BS 的情绪虐待。我们的研究结果表明，反刍和情绪虐待是两组的核心症状，而负面他人和消极自我分别对患者和对照组起着重要的中介作用。
ClinicalTrials.gov 标识符：CUH201411002。
