Liu Meng, Mo Shi-Wei, Zhou Zhi-Qin, Gao Bing-Hong
College of Physical Education and Training, Shanghai University of Sport, Shanghai 200438.
Department of Physical Education, Shenzhen University, Shenzhen 518060.
Zhongguo Ying Yong Sheng Li Xue Za Zhi. 2021 Sep;37(5):523-528. doi: 10.12047/j.cjap.6166.2021.055.
To investigate the effects of 4-week tangeretin supplementation on cortisol stress response induced by high-intensity resistance exercise. Twenty-four sprinters were paired and randomly divided into experimental group (EG) and control group (CG). EG orally took supplement with tangeretin (200 mg/day) and CG took placebo for 4 weeks. Before and after the 4-week intervention, all sprinters performed a set of high-intensity resistance exercise (shoulder press, squat, bench press and deadlift, 10 RM, 4 sets per movement) to stimulate their cortisol stress responses. Serum levels of cortisol, adreno-corticotropic hormone (ACTH), superoxide dismutase (SOD), white blood cell count (WBC) and blood glucose were obtained by collecting blood sample before the exercise (PRE), immediately after the exercise (P0), and at 10 (P10), 20 (P20), and 30 minutes (P30) after the exercise. Compared with the same period before the intervention, after the 4-week tangeretin intervention, EXP showed significantly reduced serum cortisol level at PRE (=0.017), P10 (=0.010), P20 and P30 (＜0.05 or ＜0.01), and significantly reduced WBC at PRE, ACTH at P10 (=0.037) and WBC and ACTH at P30 (＜0.05). Compared with CTROL, EXP showed significantly lower levels of the serum cortisol at PRE and P10 (＜0.05), and significantly lower levels of the ACTH (＜0.05) and WBC (＜0.01) at P30, and significantly increased level of the SOD activity at P30 (＜0.05). Tangeretin supplementation can significantly alleviate the cortisol stress response induced by high-intensity resistance exercise, inhibit the excessive secretion of cortisol, enhance antioxidant capacity, accelerate the elimination of inflammation in the body, and promote the recovery of body functions.
为研究连续4周补充橘皮素对高强度抗阻运动诱导的皮质醇应激反应的影响。将24名短跑运动员配对并随机分为实验组（EG）和对照组（CG）。实验组口服补充橘皮素（200毫克/天），对照组服用安慰剂，为期4周。在为期4周的干预前后，所有短跑运动员都进行了一组高强度抗阻运动（坐姿推举、深蹲、卧推和硬拉，10次重复最大值，每个动作4组）以刺激其皮质醇应激反应。通过在运动前（PRE）、运动后即刻（P0）以及运动后10分钟（P10）、20分钟（P20）和30分钟（P30）采集血样，测定血清皮质醇、促肾上腺皮质激素（ACTH）、超氧化物歧化酶（SOD）、白细胞计数（WBC）和血糖水平。与干预前同期相比，4周橘皮素干预后，实验组在PRE（=0.017）、P10（=0.010）、P20和P30时血清皮质醇水平显著降低（＜0.05或＜0.01），在PRE时白细胞显著降低，在P10时ACTH（=0.037）以及在P30时白细胞和ACTH显著降低（＜0.05）。与对照组相比，实验组在PRE和P10时血清皮质醇水平显著更低（＜0.05），在P30时ACTH水平显著更低（＜0.05）以及白细胞水平显著更低（＜0.01），且在P30时SOD活性水平显著升高（＜0.05）。补充橘皮素可显著减轻高强度抗阻运动诱导的皮质醇应激反应，抑制皮质醇过度分泌，增强抗氧化能力，加速体内炎症消除，并促进身体机能恢复。
