• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

巴西巴拉那州艾滋病毒/艾滋病患者接受抗逆转录病毒治疗后的病毒学成功。

Virologic success under antiretroviral therapy among people living with HIV/AIDS in the state of Paraná, Brazil.

机构信息

Universidade Federal do Paraná, Curitiba, PR, Brazil.

出版信息

Einstein (Sao Paulo). 2021 Nov 22;19:eAO5800. doi: 10.31744/einstein_journal/2021AO5800. eCollection 2021.

DOI:10.31744/einstein_journal/2021AO5800
PMID:34817033
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8687700/
Abstract

OBJECTIVE

To characterize the sociodemographic profile of the population undergoing antiretroviral treatment in the state of Paraná, Brazil, to investigate the proportion of people undergoing treatment among all those diagnosed, and to analyze the proportion of patients with suppressed viral load in different regions of the state.

METHODS

Observational descriptive and analytical study carried out with information referring to the period from January 2018 to January 2019. Data were obtained from the Sistema Informatizado de Monitoramento Clínico das Pessoas Vivendo com HIV/AIDS [Computerized System for Clinical Monitoring of People Living with HIV/AIDS] and Sistema de Controle Logístico de Medicamentos[Drug Supply Control System]. The proportion of people on antiretroviral treatment in the state and the proportion of patients with viral load ≤1,000 copies/mL and ≤50 copies/mL were calculated. The results were compared with the corresponding parameters of the World Health Organization goal 90-90-90.

RESULTS

The state of Paraná managed to reach the second and third parameters of the 90-90-90 goal of the World Health Organization. Among those diagnosed, 93.12% were on antiretroviral treatment, and 90.0% of them had a viral load below 50 copies of viral RNA/mL of blood, indicating virologic success.

CONCLUSION

The health policy aimed at the population living with HIV/AIDS, and the health services available in Paraná have been successful in parameters relevant to the control of the epidemic. However, it is necessary to ensure the diagnosis of people infected with HIV in the population.

摘要

目的

描述巴西巴拉那州接受抗逆转录病毒治疗人群的社会人口学特征,调查在所有诊断出的患者中接受治疗的比例,并分析该州不同地区病毒载量得到抑制的患者比例。

方法

这是一项观察性描述性和分析性研究,数据来源于 2018 年 1 月至 2019 年 1 月期间的信息。数据来自 Sistema Informatizado de Monitoramento Clínico das Pessoas Vivendo com HIV/AIDS(艾滋病毒/艾滋病感染者临床监测计算机化系统)和 Sistema de Controle Logístico de Medicamentos(药品供应管制系统)。计算了该州接受抗逆转录病毒治疗的人群比例,以及病毒载量≤1000 拷贝/ml 和≤50 拷贝/ml 的患者比例。将结果与世界卫生组织 90-90-90 目标的相应参数进行比较。

结果

巴拉那州设法实现了世界卫生组织 90-90-90 目标的第二和第三个参数。在诊断出的患者中,93.12%接受了抗逆转录病毒治疗,其中 90.0%的患者血液中病毒 RNA 载量低于 50 拷贝/ml,表明病毒学成功。

结论

针对艾滋病毒感染者的卫生政策以及巴拉那州现有的卫生服务在与疫情控制相关的参数方面取得了成功。然而,有必要确保对人群中感染艾滋病毒的人进行诊断。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01e7/8687700/2ce950fe74de/2317-6385-eins-19-eAO5800-gf02-pt.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01e7/8687700/6cd3d06525e3/2317-6385-eins-19-eAO5800-gf01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01e7/8687700/676771196b6f/2317-6385-eins-19-eAO5800-gf02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01e7/8687700/14c48eb71bc6/2317-6385-eins-19-eAO5800-gf01-pt.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01e7/8687700/2ce950fe74de/2317-6385-eins-19-eAO5800-gf02-pt.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01e7/8687700/6cd3d06525e3/2317-6385-eins-19-eAO5800-gf01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01e7/8687700/676771196b6f/2317-6385-eins-19-eAO5800-gf02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01e7/8687700/14c48eb71bc6/2317-6385-eins-19-eAO5800-gf01-pt.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01e7/8687700/2ce950fe74de/2317-6385-eins-19-eAO5800-gf02-pt.jpg

相似文献

1
Virologic success under antiretroviral therapy among people living with HIV/AIDS in the state of Paraná, Brazil.巴西巴拉那州艾滋病毒/艾滋病患者接受抗逆转录病毒治疗后的病毒学成功。
Einstein (Sao Paulo). 2021 Nov 22;19:eAO5800. doi: 10.31744/einstein_journal/2021AO5800. eCollection 2021.
2
Meeting the WHO 90% target: antiretroviral treatment efficacy in Poland is associated with baseline clinical patient characteristics.实现世界卫生组织90%的目标:波兰抗逆转录病毒治疗的疗效与患者基线临床特征相关。
J Int AIDS Soc. 2017 Jul 17;20(1):21847. doi: 10.7448/IAS.20.1.21847.
3
Antiretroviral drug use by individuals living with HIV/AIDS and compliance with the Clinical Protocol and Therapy Guidelines.艾滋病毒/艾滋病感染者使用抗逆转录病毒药物情况以及对临床方案和治疗指南的依从性。
Einstein (Sao Paulo). 2020 Feb 17;18:eAO4995. doi: 10.31744/einstein_journal/2020AO4995. eCollection 2020.
4
Prevalence and predictive value of intermittent viremia with combination hiv therapy.联合抗逆转录病毒疗法期间间歇性病毒血症的患病率及预测价值
JAMA. 2001 Jul 11;286(2):171-9. doi: 10.1001/jama.286.2.171.
5
Optimal monitoring strategies for guiding when to switch first-line antiretroviral therapy regimens for treatment failure in adults and adolescents living with HIV in low-resource settings.在资源匮乏地区,针对感染艾滋病毒的成人和青少年治疗失败时何时更换一线抗逆转录病毒治疗方案的最佳监测策略。
Cochrane Database Syst Rev. 2010 Apr 14(4):CD008494. doi: 10.1002/14651858.CD008494.
6
Improved virologic outcomes over time for HIV-infected patients on antiretroviral therapy in a cohort from Rio de Janeiro, 1997-2011.在 1997-2011 年来自里约热内卢的队列中,接受抗逆转录病毒治疗的 HIV 感染患者的病毒学结果随时间改善。
BMC Infect Dis. 2014 Jun 11;14:322. doi: 10.1186/1471-2334-14-322.
7
Predictors of virologic failure in HIV-1-infected patients starting highly active antiretroviral therapy in Porto Alegre, Brazil.在巴西阿雷格里港开始接受高效抗逆转录病毒治疗的HIV-1感染患者病毒学失败的预测因素。
J Acquir Immune Defic Syndr. 2005 Nov 1;40(3):324-8. doi: 10.1097/01.qai.0000182627.28595.01.
8
High rates of baseline antiretroviral resistance among HIV-infected pregnant women in an HIV referral centre in Rio de Janeiro, Brazil.巴西里约热内卢一家艾滋病转诊中心的艾滋病毒感染孕妇中,基线抗逆转录病毒药物耐药率很高。
Int J STD AIDS. 2015 Nov;26(13):922-8. doi: 10.1177/0956462414562477. Epub 2014 Dec 9.
9
Outcomes of second-line combination antiretroviral therapy for HIV-infected patients: a cohort study from Rio de Janeiro, Brazil.巴西里约热内卢一项队列研究:HIV感染患者二线联合抗逆转录病毒治疗的结果
BMC Infect Dis. 2014 Dec 19;14:699. doi: 10.1186/s12879-014-0699-5.
10
Factors Associated With Early Virological Response in HIV-Infected Individuals Starting Antiretroviral Therapy in Brazil (2014-2015): Results From a Large HIV Surveillance Cohort.巴西开始抗逆转录病毒疗法的 HIV 感染者中与早期病毒学应答相关的因素(2014-2015 年):一项大型 HIV 监测队列的结果。
J Acquir Immune Defic Syndr. 2018 Aug 1;78(4):e19-e27. doi: 10.1097/QAI.0000000000001684.

引用本文的文献

1
HIV and AIDS in the state of Paraná, Brazil, 2007-2022: trends and spatiotemporal distribution.2007 - 2022年巴西巴拉那州的艾滋病毒与艾滋病:趋势及时空分布
Rev Bras Epidemiol. 2024 Apr 19;27:e240015. doi: 10.1590/1980-549720240015. eCollection 2024.

本文引用的文献

1
Factors affecting disclosure of HIV-positive serostatus among people living with HIV/AIDS attending an antiretroviral therapy center of Eastern India.影响在印度东部接受抗逆转录病毒治疗中心治疗的艾滋病毒/艾滋病患者透露艾滋病毒阳性血清状况的因素。
Indian J Public Health. 2020 Jan-Mar;64(1):4-10. doi: 10.4103/ijph.IJPH_172_19.
2
Cascade of care for people living with HIV infection in Southern Brazil: results from a public health network.巴西南部艾滋病毒感染者的级联护理:来自公共卫生网络的结果
Cad Saude Publica. 2018 Nov 29;34(12):e00009718. doi: 10.1590/0102-311X00009718.
3
Effectiveness of antiretroviral therapy in the single-tablet regimen era.
单片复方制剂时代抗逆转录病毒疗法的有效性
Rev Saude Publica. 2018 Nov 14;52:87. doi: 10.11606/S1518-8787.2018052000399.
4
["We live on the tightrope": the experience of health professionals working with HIV/AIDS in a remote area of Northeast Brazil].["我们在钢丝绳上行走”:巴西东北部偏远地区从事艾滋病毒/艾滋病工作的卫生专业人员的经历]
Cad Saude Publica. 2018 Nov 8;34(11):e00063618. doi: 10.1590/0102-311X00063618.
5
When patients fail UNAIDS' last 90 - the "failure cascade" beyond 90-90-90 in rural Lesotho, Southern Africa: a .当患者未达到联合国艾滋病规划署的“最后90%”目标时——非洲南部莱索托农村地区90-90-90目标之外的“失败级联”:一项…… (原文似乎不完整)
J Int AIDS Soc. 2017 Jul 19;20(1):21803. doi: 10.7448/IAS.20.1.21803.
6
The HIV treatment cascade and care continuum: updates, goals, and recommendations for the future.艾滋病病毒治疗级联与照护连续体:最新情况、目标及未来建议
AIDS Res Ther. 2016 Nov 8;13:35. doi: 10.1186/s12981-016-0120-0. eCollection 2016.
7
Should viral load thresholds be lowered?: Revisiting the WHO definition for virologic failure in patients on antiretroviral therapy in resource-limited settings.是否应降低病毒载量阈值?:重新审视世界卫生组织对资源有限环境中接受抗逆转录病毒治疗患者病毒学失败的定义。
Medicine (Baltimore). 2016 Jul;95(28):e3985. doi: 10.1097/MD.0000000000003985.
8
Sexual Activity Without Condoms and Risk of HIV Transmission in Serodifferent Couples When the HIV-Positive Partner Is Using Suppressive Antiretroviral Therapy.血清学异性性伴侣中,当 HIV 阳性一方接受抑制性抗反转录病毒治疗时,无保护性行为与 HIV 传播风险
JAMA. 2016 Jul 12;316(2):171-81. doi: 10.1001/jama.2016.5148.
9
Mapping patient-identified barriers and facilitators to retention in HIV care and antiretroviral therapy adherence to Andersen's Behavioral Model.将患者确定的阻碍因素和促进因素映射到艾滋病护理留存率及抗逆转录病毒疗法依从性的安德森行为模型。
AIDS Care. 2015;27(7):817-28. doi: 10.1080/09540121.2015.1009362. Epub 2015 Feb 11.
10
Expansion of HAART coverage is associated with sustained decreases in HIV/AIDS morbidity, mortality and HIV transmission: the "HIV Treatment as Prevention" experience in a Canadian setting.高效抗逆转录病毒治疗(HAART)覆盖范围的扩大与艾滋病毒/艾滋病的发病率、死亡率持续下降以及艾滋病毒传播减少相关:加拿大的“以治疗预防艾滋病毒”经验。
PLoS One. 2014 Feb 12;9(2):e87872. doi: 10.1371/journal.pone.0087872. eCollection 2014.