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虾青素:一种来自微藻的超级抗氧化剂及其治疗潜力。

Astaxanthin: A super antioxidant from microalgae and its therapeutic potential.

作者信息

Kumar Satish, Kumar Rakesh, Kumari Anju, Panwar Anil

机构信息

Department of Microbiology, College of Basic Sciences and Humanities, CCS Haryana Agricultural University, Hisar, India.

Centre of Food Science and Technology, CCS Haryana Agricultural University, Hisar, India.

出版信息

J Basic Microbiol. 2022 Sep;62(9):1064-1082. doi: 10.1002/jobm.202100391. Epub 2021 Nov 24.

Abstract

Astaxanthin is a ketocarotenoid, super antioxidant molecule. It has higher antioxidant activity than a range of carotenoids, thus has applications in cosmetics, aquaculture, nutraceuticals, therapeutics, and pharmaceuticals. Naturally, it is derived from Haematococcus pluvialis via a one-stage process or two-stage process. Natural astaxanthin significantly reduces oxidative and free-radical stress as compared to synthetic astaxanthin. The present review summarizes all the aspects of astaxanthin, including its structure, chemistry, bioavailability, and current production technology. Also, this paper gives a detailed mechanism for the potential role of astaxanthin as nutraceuticals for cardiovascular disease prevention, skin protection, antidiabetic and anticancer, cosmetic ingredient, natural food colorant, and feed supplement in poultry and aquaculture. Astaxanthin is one of the high-valued microalgae products of the future. However, due to some risks involved or not having adequate research in terms of long-term consumption, it is still yet to be explored by food industries. Although the cost of naturally derived astaxanthin is high, it accounts for only a 1% share in total astaxanthin available in the global market. Therefore, scientists are looking for ways to cut down the cost of natural astaxanthin to be made available to consumers.

摘要

虾青素是一种酮类胡萝卜素,即超级抗氧化分子。它比一系列类胡萝卜素具有更高的抗氧化活性,因此在化妆品、水产养殖、营养保健品、治疗学和制药领域都有应用。天然虾青素可通过一步法或两步法从雨生红球藻中提取。与合成虾青素相比,天然虾青素能显著降低氧化应激和自由基应激。本综述总结了虾青素的各个方面,包括其结构、化学性质、生物利用度和当前的生产技术。此外,本文详细阐述了虾青素作为营养保健品在预防心血管疾病、保护皮肤、抗糖尿病和抗癌、化妆品成分、天然食品色素以及家禽和水产养殖饲料添加剂方面潜在作用的机制。虾青素是未来高价值的微藻产品之一。然而,由于长期食用存在一些风险或缺乏充分研究,食品行业尚未对其进行探索。尽管天然来源的虾青素成本很高,但在全球市场上可获得的虾青素总量中,它仅占1%的份额。因此,科学家们正在寻找降低天然虾青素成本的方法,以便让消费者能够使用。

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