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巴西先天性梅毒临床特征的趋势分析,2009-2018 年。

Trend analysis of clinical aspects of congenital syphilis in Brazil, 2009-2018.

机构信息

Universidade Federal de Alagoas, Nucleus of Studies in Social and Preventive Medicine - Arapiraca (AL), Brazil.

出版信息

Rev Assoc Med Bras (1992). 2021 Jul;67(7):991-996. doi: 10.1590/1806-9282.20210432.

Abstract

INTRODUCTION

Congenital syphilis is caused by the vertical transmission of bacteria, Treponema pallidum, from nontreated or inappropriately treated pregnant to the fetus.

OBJECTIVE

To evaluate the clinical aspects of Congenital syphilis in Brazil, between 2009-2018.

METHOD

It is an analytical cross-sectional study whose data were collected from the Department of Chronical Conditions and Sexually Transmitted Infections of Brazilian Health Ministry. Clinical variables were analyzed using the software Joinpoint Regression, which makes a segmented linear regression.

RESULTS

In the study period, 156,969 cases of Congenital syphilis and 1642 deaths by this disease were reported. The trend analysis indicates growing in diagnosis of maternal syphilis during prenatal care, appropriate treatment of pregnant, realization of prenatal care, maternal partner treatment, diagnosis of syphilis in children under seven days, and diagnosis of recent syphilis.

CONCLUSIONS

Although the trend analysis presents relative improvement in Congenital syphilis panorama in Brazil, the disease still related to high numbers of evitable perinatal morbidity and mortality. Therefore, the prenatal assistance with quality is fundamental to have a possible change in this field in the country.

摘要

引言

先天性梅毒是由未经治疗或治疗不当的孕妇垂直传播梅毒螺旋体引起的。

目的

评估 2009 年至 2018 年巴西先天性梅毒的临床特征。

方法

这是一项分析性的横断面研究,数据来自巴西卫生部慢性病和性传播感染司。使用 Joinpoint Regression 软件对临床变量进行分析,该软件进行分段线性回归。

结果

在研究期间,共报告了 156969 例先天性梅毒病例和 1642 例由该病导致的死亡。趋势分析表明,产前保健中梅毒产妇的诊断、孕妇的适当治疗、产前保健的实施、性伴侣的治疗、7 天以下儿童梅毒的诊断以及近期梅毒的诊断均有所增加。

结论

尽管趋势分析表明巴西先天性梅毒的情况有所改善,但该病仍与较高的围产期发病率和死亡率相关。因此,提供高质量的产前保健对于该国在该领域可能发生的变化至关重要。

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