Kim Youngha, Kang Danbee, Kang Eunjee, Lim Jihyun, Kim Sooyeon, Nam Heesu, Shim Sungkeun, Lee Mangyeong, Moon Young-Wan, Lim Seung-Jae, Sung Ki-Sun, Cho Juhee
Center for Clinical Epidemiology, Samsung Medical Center, Seoul, Republic of Korea.
Department of Clinical Research Design and Evaluation, SAIHST, Sungkyunkwan University, 81 Irwon-ro, Gangnam-Gu, 06351, Seoul, South Korea.
BMC Sports Sci Med Rehabil. 2021 Nov 24;13(1):148. doi: 10.1186/s13102-021-00374-1.
Patients with lower extremity problems (LEP) commonly experience functional loss, pain, decreased range of motion, inadequacy in daily living activities, and structural change in radiographic evaluations. However, the traditional patient-reported outcome measurement which focused on symptoms, had a limited scope of applicability. This study aimed to validate the psychometric properties of the Korean version of PROMIS-29 Profile v2.1 (K-PROMIS-29 V2.1), a multi-dimensional measure for assessing generic profile health-related quality-of-life (HRQoL) in a sample of patients with lower extremity problems (LEP).
Participants were recruited from the orthopedic outpatient clinics at the Samsung Medical Center in Seoul, South Korea from September to October 2018. Participants completed a survey questionnaire that included the K-PROMIS-29 V2.1 and the SF-36v2. Principal component analysis (PCA) and confirmatory factor analysis (CFA) and Pearson's correlations were used to evaluate the reliability and validity of the K-PROMIS-29 V2.1.
A total of 299 participants were enrolled in the study and 258 (86%) completed the study questionnaire. The mean age (SD) of the participants was 56.6 (14.5) and 32.3%, 29.8, and 25.2% of the study participants visited outpatient clinics for foot, knee, and hip problems respectively. The Cronbach's alpha coefficients of 7 sub-domains in K-PROMIS-29 V2.1 ranged from 0.80 to 0.95, indicating satisfactory internal consistency. In CFA, the goodness-of-fit indices were high (CFI = 0.937 and SRMR = 0.061). High to moderate correlations were found between comparable subscales of the K-PROMIS-29 V2.1 and subscales of the SF-36v2 (r = 0.55-0.70).
The K-PROMIS-29 V2.1 is a reliable and valid measure for assessing a broad range of health-related quality-of-life domains in patients with LEP. It would reflect the real-life symptoms experienced by patients with LEP.
下肢问题（LEP）患者通常会经历功能丧失、疼痛、活动范围减小、日常生活活动能力不足以及影像学评估中的结构变化。然而，传统的患者报告结局测量方法侧重于症状，适用范围有限。本研究旨在验证韩国版PROMIS-29简表v2.1（K-PROMIS-29 V2.1）的心理测量特性，这是一种用于评估下肢问题（LEP）患者样本中一般健康相关生活质量（HRQoL）的多维测量工具。
2018年9月至10月，从韩国首尔三星医疗中心的骨科门诊招募参与者。参与者完成了一份调查问卷，其中包括K-PROMIS-29 V2.1和SF-36v2。主成分分析（PCA）、验证性因子分析（CFA）和Pearson相关性用于评估K-PROMIS-29 V2.1的信度和效度。
共有299名参与者纳入研究，258名（86%）完成了研究问卷。参与者的平均年龄（标准差）为56.6（14.5）岁，分别有32.3%、29.8%和25.2%的研究参与者因足部、膝盖和髋部问题就诊于门诊。K-PROMIS-29 V2.1中7个亚领域的Cronbach's alpha系数范围为0.80至0.95，表明内部一致性良好。在CFA中，拟合优度指标较高（CFI = 0.937，SRMR = 0.061）。K-PROMIS-29 V2.1的可比子量表与SF-36v2的子量表之间存在高到中度的相关性（r = 0.55 - 0.70）。
K-PROMIS-29 V2.1是一种可靠且有效的测量工具，用于评估LEP患者广泛的健康相关生活质量领域。它能反映LEP患者所经历的现实生活中的症状。
