Michigan State University, East Lansing, Michigan.
University of Nebraska - Lincoln, Lincoln, Nebraska.
J Voice. 2024 May;38(3):800.e13-800.e26. doi: 10.1016/j.jvoice.2021.10.004. Epub 2021 Nov 21.
This study evaluated the amount of phonatory activity of Persons with Parkinson disease (PwPD) compared to adults without Parkinson's disease measured over 3 days. The relationship between the amount of phonatory activity and Voice Handicap Index (VHI) total score was assessed as were differences in voicing activity across 3 days of data collection.
Fifteen PwPD receiving dopaminergic medication and fifteen age and sex matched adults without Parkinson's disease completed the VHI and then wore a VocaLog vocal monitor (VM) for 3 consecutive days. From the VM data, the number of 1-second windows with dB sound pressure level > 0 were summed as a measure of phonatory activity (PA) and reported relative to the time the VM was worn (%PA).
The percentage of time the VM was worn did not differ between groups or across days. The PwPD had statistically significantly fewer minutes of PA per day than controls (F = 21.782, P < 0.001) by 54 minutes on average. The %PA also differed significantly (F = 31.825, P < 0.001) with a mean of 11.1% for PwPD and 18.6% for controls. Neither PA nor %PA differed across the 3 days of vocal monitoring. VHI total score was significantly correlated with PA (r = -0.436, P = 0.016) and %PA (r = -0.534, P = 0.002) for all participants.
The results indicate that PwPD engaged in less verbal communication in their daily environment compared to adults without Parkinson's disease. The findings support reports in the literature indicating that PwPD often have reduced communication participation. Measures such as %PA could serve as a quantifiable metric in future studies assessing communication changes in PwPD as a function of disease progression or therapeutic interventions.
本研究评估了与未患帕金森病的成年人相比，帕金森病患者（PwPD）在 3 天内的发音活动量。评估了发音活动量与嗓音障碍指数（VHI）总分之间的关系，以及在 3 天的数据收集过程中，发音活动在不同时间的差异。
15 名正在服用多巴胺能药物的 PwPD 和 15 名年龄和性别匹配的未患帕金森病的成年人完成了 VHI，然后连续 3 天佩戴 VocaLog 发声监测仪（VM）。从 VM 数据中，将声压级大于 0 的 1 秒窗口的数量相加，作为发音活动（PA）的测量值，并报告相对于 VM 佩戴时间的比例（%PA）。
VM 佩戴时间在组间和天内没有差异。PwPD 每天的 PA 分钟数明显少于对照组（F=21.782，P<0.001），平均少 54 分钟。%PA 也有显著差异（F=31.825，P<0.001），PwPD 的平均值为 11.1%，对照组为 18.6%。在 3 天的发声监测中，PA 和%PA 均无差异。所有参与者的 VHI 总分与 PA（r=-0.436，P=0.016）和%PA（r=-0.534，P=0.002）均呈显著相关。
结果表明，与未患帕金森病的成年人相比，PwPD 在日常生活中进行的言语交流较少。这些发现支持了文献中的报告，表明 PwPD 经常减少沟通参与。像%PA 这样的措施可以作为未来研究中评估 PwPD 随疾病进展或治疗干预而发生的沟通变化的一个可量化指标。
