Jamil Md, Bhattacharya Prasanta K, Barman Bhupen, Topno Noor, Barman Himesh, Nongpiur Vijay N, War Gwenette, Hynniewta Yasmeen, Saikia Bishwajeet, Naku Narang
Department of General Medicine, North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences, Shillong, IND.
Internal Medicine, North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences, Shillong, IND.
Cureus. 2021 Oct 19;13(10):e18881. doi: 10.7759/cureus.18881. eCollection 2021 Oct.
Background and objective The coronavirus disease 2019 (COVID-19) outbreak, which was first detected in Wuhan, China, has turned into a rapidly spreading global healthcare crisis. The clinical and laboratory features of COVID-19 are associated with significant regional variations. In this study, we aimed to describe the clinical and demographic profile of COVID-19 patients from a tertiary care hospital in Northeast India. Materials and methods This was a hospital-based cross-sectional study that included all laboratory-confirmed COVID-19 cases admitted to the institution from 1st July to 31st October 2020. The information was collected on a predesigned proforma, which included patients' demographic profiles, clinical presentations, and outcomes as per treatment by trained doctors. Results The study included 180 laboratory-confirmed COVID-19 cases. A history of contact with laboratory-confirmed COVID-19-affected individuals was found in 92 (51.1%) patients. The median age of the patients was 37.17 years (range: 18-80 years), and there were 104 (57.78%) males in the cohort. Of the total enrolled patients, 102 (56.67%) were asymptomatic from the time of exposure till their admission. The common presenting complaints were fever (n=55, 70.51%), cough (n=42, 53.85%), and shortness of breath (n=32, 42.02%). The case fatality rate among the admitted cases was 15%. Comorbidities were found in 84 (46.67%) patients with the most common one being diabetes mellitus (n=31, 36.9%) followed by hypertension (n=29, 34.52%). Patients with advanced age (more than 60 years) and coexisting comorbidities were at higher risk of progression of disease and death. Conclusion The COVID-19 pandemic is not only a huge burden on healthcare facilities but also a significant cause of disruption in societies globally. The majority of the patients with COVID-19 infection presenting to our hospital were young and asymptomatic. Patients of advanced age with comorbidities were found to have more complications. An analysis of the trends related to COVID-19 in different hospital and institutional settings will help to achieve better preparedness and lead to improved patient care to combat the COVID-19 pandemic in a more efficient manner.
背景与目的 2019 冠状病毒病（COVID-19）疫情最初在中国武汉被发现，现已演变成一场迅速蔓延的全球医疗危机。COVID-19 的临床和实验室特征存在显著的地区差异。在本研究中，我们旨在描述印度东北部一家三级医疗医院中 COVID-19 患者的临床和人口统计学特征。材料与方法 这是一项基于医院的横断面研究，纳入了 2020 年 7 月 1 日至 10 月 31 日期间该机构收治的所有实验室确诊的 COVID-19 病例。信息通过预先设计的表格收集，内容包括患者的人口统计学特征、临床表现以及经培训的医生根据治疗情况记录的预后。结果 该研究纳入了 180 例实验室确诊的 COVID-19 病例。92 例（51.1%）患者有与实验室确诊的 COVID-19 感染者接触史。患者的中位年龄为 37.17 岁（范围：18 - 80 岁），队列中有 104 例（57.78%）男性。在所有登记患者中，102 例（56.67%）从接触病毒到入院期间无症状。常见的就诊主诉为发热（n = 55，70.51%）、咳嗽（n = 42，53.85%）和呼吸急促（n = 32，42.02%）。入院病例的病死率为 15%。84 例（46.67%）患者有合并症，最常见的是糖尿病（n = 31，36.9%），其次是高血压（n = 29，34.52%）。高龄（60 岁以上）且有合并症的患者疾病进展和死亡风险更高。结论 COVID-19 大流行不仅给医疗设施带来巨大负担，也是全球社会混乱的一个重要原因。到我院就诊的大多数 COVID-19 感染患者年轻且无症状。有合并症的高龄患者并发症更多。分析不同医院和机构环境中与 COVID-19 相关的趋势将有助于更好地做好准备，并以更有效的方式改善患者护理以应对 COVID-19 大流行。
