Waqar Syed Hamza Bin, Khan Anosh Aslam, Coca Guzman Juan, Gottesman Susan Rs, McFarlane Isabel
Internal Medicine, State University of New York Downstate Health Sciences University, New York, USA.
Internal Medicine, Dow University of Health Sciences, Karachi, PAK.
Cureus. 2021 Oct 19;13(10):e18893. doi: 10.7759/cureus.18893. eCollection 2021 Oct.
Non-Hodgkin lymphoma is one of the most common hematological malignancies having both nodal and extranodal sites of involvement. The thyroid gland is one of the rarest primary sites. Most cases of primary thyroid lymphoma are diffuse large B-cell in nature; thus, aggressive and in extreme cases can rapidly lead to airway compromise, especially in patients who have been living with goiter for years. We present one such case of a 64-year-old female who presented with signs of airway compromise, requiring emergent airway intubation and surgical debulking. She was treated with emergent chemotherapy (DA-EPOCH-R regimen), without radiotherapy and this resulted in complete remission.
非霍奇金淋巴瘤是最常见的血液系统恶性肿瘤之一，可累及淋巴结和结外部位。甲状腺是最罕见的原发部位之一。大多数原发性甲状腺淋巴瘤本质上是弥漫性大B细胞淋巴瘤；因此，病情凶险，在极端情况下可迅速导致气道受压，尤其是多年患有甲状腺肿的患者。我们报告了这样一例64岁女性患者，她出现气道受压症状，需要紧急气管插管和手术减瘤。她接受了紧急化疗（DA-EPOCH-R方案），未进行放疗，最终实现完全缓解。
