Giovane Richard, Campbell Jessica
Family Medicine, University of Alabama (UAB), Greenville, USA.
Family Medicine, Jackson Hospital, Greenville, USA.
Cureus. 2021 Oct 22;13(10):e18977. doi: 10.7759/cureus.18977. eCollection 2021 Oct.
Vaccine-induced immune thrombotic thrombocytopenia (VITT) is a rare but potentially life-threatening side effect that has only been observed in adenovirus-based vaccines for coronavirus disease 2019 (COVID-19). VITT is an immune-mediated condition that generally presents within five to 10 days post-vaccination with thrombosis, thrombocytopenia, and coagulation abnormalities. A diagnosis of VITT is made clinically and through laboratory testing. Although VITT is an important differential to consider, it is believed that more emphasis should be placed on vaccination due to the safety and efficacy in overcoming COVID-19.
疫苗诱导的免疫性血栓性血小板减少症(VITT)是一种罕见但可能危及生命的副作用,仅在用于2019冠状病毒病(COVID-19)的腺病毒疫苗中观察到。VITT是一种免疫介导的病症,通常在接种疫苗后五至十天内出现血栓形成、血小板减少和凝血异常。VITT的诊断通过临床和实验室检测进行。尽管VITT是一个需要考虑的重要鉴别诊断,但由于疫苗在克服COVID-19方面的安全性和有效性,人们认为应更加重视接种疫苗。