Acute Medical Unit, Royal Perth Hospital, Perth, Western Australia, Australia
Gastroenterology, Royal Perth Hospital, Perth, Western Australia, Australia.
BMJ Case Rep. 2023 May 5;16(5):e251180. doi: 10.1136/bcr-2022-251180.
As COVID-19 vaccination becomes widely available and administered globally, there have been several reports of side effects attributed to the vaccine. This report highlights a patient who developed stroke 2 days following the administration of the COVID-19 vaccine, although its association remains uncertain. A man in his late 30s developed acute neurological symptoms 2 days after receiving the booster dose of the BNT162b2 (Pfizer-BioNTech) mRNA COVID-19 vaccine. History and neurological examination suggested a posterior circulation stroke, which was confirmed by MRI, as a right-sided posterior inferior cerebellar artery stroke. Full workup did not suggest other causes of the stroke. Due to the patient's age and well-controlled risk factors, it was presumed to be a rare adverse effect of the vaccine. Medical management with aspirin, statin therapy and rehabilitation led to the improvement of symptoms and enabled ongoing restoration of function. Further cases of stroke following administration of COVID-19 vaccine have been documented in the literature, but the association is yet to be established.
随着 COVID-19 疫苗在全球范围内广泛接种和使用，已经有几起因疫苗引起的副作用报告。本报告重点介绍了一名患者在接种 COVID-19 疫苗后 2 天发生中风的情况，尽管其相关性尚不确定。一名 30 多岁的男性在接受 BNT162b2（辉瑞-生物科技）mRNA COVID-19 疫苗加强针后 2 天出现急性神经系统症状。病史和神经系统检查提示后循环中风，MRI 证实为右侧小脑后下动脉中风。全面检查未提示中风的其他原因。由于患者年龄较轻且危险因素得到良好控制，因此推测这是疫苗的罕见不良反应。给予阿司匹林、他汀类药物治疗和康复治疗后症状得到改善，并持续恢复功能。文献中已经记录了 COVID-19 疫苗接种后发生的其他中风病例，但关联尚未确定。
