Mushtaq Sarah, Prabakaran Sabrina, Elharake Maher, Mirza Sayeef, Ravindran Adharsh, Faramand Rawan, Sokol Lubomir
Department of Internal Medicine, University of South Florida, Tampa, FL.
Department of Internal Medicine, University of Buffalo, NY.
ACG Case Rep J. 2021 Nov 19;8(11):e00698. doi: 10.14309/crj.0000000000000698. eCollection 2021 Nov.
Primary effusion lymphoma (PEL) is a rare AIDS-associated non-Hodgkin lymphoma, growing in the serous body cavities as a lymphomatous effusion. The endoscopic features of PEL can mimic Kaposi sarcoma (KS). We present a case where PEL presented as small intestinal masses which had a similar macroscopic appearance to KS. Endoscopic evaluation was used with biopsies which confirmed the diagnosis of PEL. PEL is a differential of gastrointestinal KS. Accurate diagnosis is crucial for prognostication in these patients. Our case emphasizes that PEL presenting as intestinal tumors can mimic KS macroscopically. Although treatment for PEL and KS includes standard chemotherapy with concurrent antiretroviral therapy, early detection of PEL can improve overall survival in these patients.
原发性渗出性淋巴瘤（PEL）是一种罕见的与艾滋病相关的非霍奇金淋巴瘤，以淋巴瘤性渗出液的形式在浆膜体腔中生长。PEL的内镜特征可模仿卡波西肉瘤（KS）。我们报告一例PEL表现为小肠肿块，其宏观外观与KS相似。通过内镜评估并结合活检确诊为PEL。PEL是胃肠道KS的鉴别诊断之一。准确诊断对这些患者的预后至关重要。我们的病例强调，表现为肠道肿瘤的PEL在宏观上可模仿KS。虽然PEL和KS的治疗包括标准化疗及同时进行抗逆转录病毒治疗，但早期发现PEL可提高这些患者的总体生存率。
