Coffey J Calvin, Byrnes Kevin G, Walsh Dara John, Cunningham Robert Martin
Department of Surgery, University Hospital Limerick, Limerick, Ireland; School of Medicine, University of Limerick, Limerick, Ireland.
School of Medicine, University of Limerick, Limerick, Ireland.
Lancet Gastroenterol Hepatol. 2022 Jan;7(1):96-106. doi: 10.1016/S2468-1253(21)00179-5. Epub 2021 Nov 22.
Over the past 5 years, systematic investigation of the mesenteric organ has expanded and shown that the mesentery is the organ in and on which all abdominal digestive organs develop and remain connected to. In turn, this observation has clarified the anatomical foundation of the abdomen and the fundamental order at that level. Findings related to the shape and development of the mesentery have illuminated its function, advancing our understanding of the pathobiology, diagnosis, and treatment of several abdominal and systemic diseases. Inclusion of the mesentery in surgical resections alters the course of benign and malignant diseases. Mesenteric-based scoring systems can enhance the radiological interpretation of abdominal disease. Emerging findings reconcile observations across scientific and clinical fields and have been assimilated into reference curricula and practice guidelines. This Review summarises the developmental, anatomical, and clinical advances made since the mesentery was redesignated as an organ in 2016.
在过去5年里，对肠系膜器官的系统研究不断扩展，并表明肠系膜是所有腹部消化器官在其中发育并与之保持相连的器官。反过来，这一观察结果阐明了腹部的解剖学基础以及该层面的基本秩序。与肠系膜形状和发育相关的研究结果揭示了其功能，增进了我们对多种腹部和全身性疾病的病理生物学、诊断及治疗的理解。在手术切除中纳入肠系膜会改变良性和恶性疾病的病程。基于肠系膜的评分系统可增强对腹部疾病的影像学解读。新出现的研究结果使不同科学和临床领域的观察结果相互协调，并已被纳入参考课程和实践指南。本综述总结了自2016年肠系膜被重新认定为一个器官以来在发育、解剖学和临床方面取得的进展。
