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35 岁时童年和成年早期癌症存活者的家庭形成和社会经济地位:基于登记的队列研究。

Family Formation and Socio-Economic Status among 35-Year-Old Men Who Have Survived Cancer in Childhood and Early Adulthood: A Register-Based Cohort Study.

机构信息

Department of Obstetrics and Gynaecology, Fertility Clinic Section 455, Hvidovre University Hospital, Hvidovre, Denmark.

Department of Public Health, University of Copenhagen, Copenhagen, Denmark.

出版信息

Oncol Res Treat. 2022;45(3):102-111. doi: 10.1159/000520365. Epub 2021 Nov 25.

Abstract

INTRODUCTION

The number of children and young adults who survive cancer has steadily increased over the past decades. Consequently, life circumstances after cancer have gained increasing importance. The aim of this study was to explore family formation and socio-economic status among 35-year-old men having survived cancer in childhood or early adulthood compared to an age-matched comparison group.

METHODS

This study is a national, register-based cohort study among 35-year-old men. Men diagnosed with cancer in childhood and early adulthood were registered between 1978 and 2016. At the time of diagnosis, each patient was randomly matched with 150 men without cancer from the background population within the same birth year. Those still alive at the age of 35 years were included in the study population.

RESULTS

The study population consisted of 4,222 men diagnosed with cancer in childhood or early adulthood and 794,589 men in the age-matched comparison group. Men who have survived cancer during childhood or early adulthood have a reduced probability of having children, and lower probability of getting married or of cohabitation than those from an age-matched comparison group. Men who have survived CNS cancer also have a lower probability of having a higher education than high school and a higher probability of being outside the workforce than those from an age-matched comparison group.

DISCUSSION/CONCLUSION: Many men who have survived cancer during childhood or early adulthood are influenced by their cancer later in life, which was apparent in family formation, educational achievements, and labour market attachment. Continued focus on rehabilitation and needs for support among the male survivors of childhood and youth cancer is warranted.

摘要

简介

在过去几十年中,幸存癌症的儿童和年轻人的数量稳步增加。因此,癌症后的生活状况变得越来越重要。本研究的目的是探讨 35 岁男性在儿童期或成年早期幸存癌症后的家庭形成和社会经济地位,与年龄匹配的对照组进行比较。

方法

这是一项全国范围内基于登记的队列研究,涉及 35 岁的男性。在儿童期和成年早期被诊断患有癌症的男性于 1978 年至 2016 年期间进行了登记。在诊断时,每位患者都与同一年出生的背景人群中没有癌症的 150 名男性进行随机匹配。在 35 岁时仍然存活的患者被纳入研究人群。

结果

研究人群包括 4222 名在儿童期或成年早期被诊断患有癌症的男性和 794589 名年龄匹配的对照组男性。在儿童期或成年早期幸存癌症的男性生育子女的可能性较低,结婚或同居的可能性也低于年龄匹配的对照组男性。患有中枢神经系统癌症的男性接受高等教育的可能性也较低,而未参加工作的可能性则高于年龄匹配的对照组男性。

讨论/结论:许多在儿童期或成年早期幸存癌症的男性在以后的生活中会受到癌症的影响,这在家庭形成、教育成就和劳动力市场参与方面表现明显。需要继续关注儿童和青年癌症幸存者的康复和支持需求。

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