高血清 copeptin 可能是 1 型糖尿病无症状患者颈动脉内膜中层厚度增加的标志物。

High serum copeptin may be a marker of an increased carotid intima-media thickness in asymptomatic patients with type 1 diabetes.

机构信息

Department of Endocrinology and Nutrition, Hospital Universitario Ramón y Cajal & Universidad de Alcalá, Madrid & Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS) & CIBER Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Madrid, Spain; Diabetes, Obesity and Human Reproduction Research Group, Hospital Universitario Ramón y Cajal & Universidad de Alcalá, Madrid & Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS) & CIBER Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Madrid, Spain.

Diabetes, Obesity and Human Reproduction Research Group, Hospital Universitario Ramón y Cajal & Universidad de Alcalá, Madrid & Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS) & CIBER Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Madrid, Spain.

出版信息

J Diabetes Complications. 2022 Jan;36(1):108085. doi: 10.1016/j.jdiacomp.2021.108085. Epub 2021 Nov 11.

DOI:10.1016/j.jdiacomp.2021.108085

PMID:34823978

Abstract

We aimed to study the association of copeptin with carotid intima-media thickness in 60 patients with type 1 diabetes (T1DM-patients). Our results suggest that copeptin might improve the stratification of cardiovascular risk in T1DM-patients. Further research is needed to determine the value in identifying carotid disease of this biochemical marker.

摘要

我们旨在研究 60 例 1 型糖尿病（T1DM 患者）患者中 copeptin 与颈动脉内膜中层厚度的关系。我们的研究结果表明，copeptin 可能改善 T1DM 患者的心血管风险分层。需要进一步研究来确定该生化标志物在识别颈动脉疾病方面的价值。