Department of Internal Medicine, Dankook University College of Medicine, Cheonan, Korea.
Department of Pathology, Dankook University College of Medicine, Cheonan, Korea.
Korean J Gastroenterol. 2021 Nov 25;78(5):300-304. doi: 10.4166/kjg.2021.125.
Neuroendocrine tumors (NETs) can arise throughout the body. Most NETs in the liver are metastatic tumors; primary hepatic NET (PHNET) is extremely rare. A diagnosis of PHNET is very difficult. No single modality can diagnose PHNET by itself, and it often resembles other hypervascular masses of the liver. This paper reports the case of a 51-year old female with a large hepatic mass. Unlike most of PHNETs reported previously, it was composed of a solid mass with mainly multiple cystic lesions, which led to an erroneous diagnosis of hepatic mucinous cystadenoma or cystadenocarcinoma. PHNET with cystic lesions is extremely rare, and the features are not well studied. This case may help physicians suspect PHNET in a differential diagnosis of an atypical hepatic mass.
神经内分泌肿瘤（NET）可发生于全身各处。肝脏内的大多数 NET 为转移性肿瘤；原发性肝神经内分泌肿瘤（PHNET）极其罕见。PHNET 的诊断极具挑战性。没有任何单一方法可单独诊断 PHNET，其通常与其他肝脏富血供性肿块相似。本文报道了 1 例 51 岁女性的巨大肝肿块病例。与既往报道的大多数 PHNET 不同，该肿瘤主要由实性肿块伴多发囊性病变组成，这导致误诊为肝黏液性囊腺瘤或囊腺癌。伴有囊性病变的 PHNET 非常罕见，其特征尚未得到充分研究。该病例可能有助于医生在对非典型肝肿块进行鉴别诊断时怀疑 PHNET。
