Department of Epizootology, Radiobiology, and Pharmacology, I.I. Ivanov Kursk State Agricultural Academy. 305021, Kursk, K. Marxa Str., 70.
Candidate of Agricultural Sciences, Kursk Institute of Cooperation (branch) of BUKEP. 305004 Kursk, Radishcheva Str., 116.
Arch Razi Inst. 2021 Sep 1;76(3):649-657. doi: 10.22092/ari.2021.355354.1676. eCollection 2021 Summer.
Testes have several primary functions, such as male gametes production (spermatozoa) and secretion of several endocrine factors, including the production of steroid and protein hormones which facilitate elements in the healthy reproductive function of mammals. The potential of an animal functional endocrine reservoir could be an interesting finding in animal reproduction management. Therefore, the current study aimed to analyze the functional endocrine reserves of testes in 12- and 18-month-old boars of four different boar breeds, namely Large White, Landrace, Duroc, and Tempo, as the animal model in this research (n=10). To determine the functional endocrine reserves of the testes at 12 and 18 months of age, boars received injections of human chorionic gonadotropin (hCG) 3 times every 72 hours. Testosterone was measured in blood samples (10 mL) taken from the jugular vein before the administration of hCG as well as 2, 12, 24, 48, and 72 hours after administration of each of three hCG injections. The index of endocrine activity of the testes was determined by the formula: I = T -T / T , where I is the index of endocrine activity of the testes, T is the testosterone concentration before the administration of hCG, and T is the maximum testosterone concentration after the third administration of hCG. The effects of the hCG injection on boar testes at different age periods indicated that the testes of Large White and Duroc boars have higher potential endocrine reserves compared with the Landrace and Tempo breeds.
睾丸具有几个主要功能，如产生雄性配子（精子）和分泌几种内分泌因子，包括类固醇和蛋白质激素的产生，这些激素有助于哺乳动物的生殖功能健康。动物功能性内分泌储备的潜力可能是动物繁殖管理中的一个有趣发现。因此，本研究旨在分析 12 月龄和 18 月龄 4 个不同品种公猪（大白猪、长白猪、杜洛克猪和皮特兰猪）睾丸的功能性内分泌储备，这些动物作为本研究的模型（n=10）。为了确定 12 月龄和 18 月龄时睾丸的功能性内分泌储备，公猪每隔 72 小时接受 3 次人绒毛膜促性腺激素（hCG）注射。在 hCG 给药前，从颈静脉采集 10 mL 血液样本，测量睾酮浓度，然后在 hCG 给药后 2、12、24、48 和 72 小时再次采血。睾丸内分泌活动指数通过公式计算：I = T-T/T，其中 I 是睾丸内分泌活动指数，T 是 hCG 给药前的睾酮浓度，T 是第三次 hCG 给药后的最大睾酮浓度。hCG 注射对公猪不同年龄睾丸的影响表明，与长白猪和皮特兰猪相比，大白猪和杜洛克猪的睾丸具有更高的潜在内分泌储备。
