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特发性晶状体表面新生血管形成:一种不寻常的表现。

Idiopathic lenticular surface neovascularization: An unusual presentation.

作者信息

Soman Manoj, Nair Indu J, Nadig Ramya R, Sheth Jay U, Nair Unnikrishnan

机构信息

Vitreoretinal Services, Chaithanya Eye Hospital and Research Institute, Trivandrum, India.

Chaithanya Innovation in Technology and Eyecare (Research), Trivandrum, India.

出版信息

Am J Ophthalmol Case Rep. 2021 Nov 10;24:101231. doi: 10.1016/j.ajoc.2021.101231. eCollection 2021 Dec.

Abstract

PURPOSE

To present a case of posterior lenticular surface neovascularization in the absence of any ocular or systemic pathology.

OBSERVATIONS

A 29-year-old asymptomatic male was detected with the right eye (OD) posterior lenticular surface neovascularization extending for six-clock hours in the temporal portion along with the presence of mild posterior capsular haze. His best-corrected visual acuity was 20/25 in OD and 20/20 in the left eye (OS). No additional abnormality was identified in the remainder of the OD anterior segment and the fundus respectively. OS evaluation was unremarkable. OD imaging including B-scan ultrasonography and ultrasound biomicroscopy (UBM) were essentially normal. The anterior segment optical coherence tomography (AS-OCT) thickened lens capsule with a dense hyperreflective layer adhered to its posterior surface and separating from the capsule in the periphery. Few hyperreflective dots were visible posterior to the ciliary body although no CB thickening was noted. No systemic abnormality was detected. The patient is being managed conservatively and has shown no signs of progression of the neovascularization over six months.

CONCLUSIONS AND IMPORTANCE

This is the first reported case of an isolated idiopathic posterior lenticular surface neovascularization occurring in an otherwise healthy patient. Although an unspecified breach in the posterior capsule or undetermined cyclitis can trigger such neovascularization, further histopathological studies of the capsular biopsy and ciliary body can provide better insight into its etiopathogenesis. Additionally, considering the asymptomatic nature of the condition, these patients can be observed and closely monitored.

摘要

目的

报告一例在无任何眼部或全身病变情况下出现的晶状体后表面新生血管形成病例。

观察结果

一名29岁无症状男性被检测出右眼(OD)晶状体后表面新生血管形成,在颞侧延伸达六个钟点范围,并伴有轻度后囊膜混浊。其右眼最佳矫正视力为20/25,左眼(OS)为20/20。右眼前段其余部分和眼底分别未发现其他异常。左眼检查未见明显异常。右眼的成像检查,包括B超超声检查和超声生物显微镜检查(UBM)基本正常。前段光学相干断层扫描(AS-OCT)显示晶状体囊膜增厚,后表面附着一层致密的高反射层,周边与囊膜分离。睫状体后方可见少量高反射点,但未发现睫状体增厚。未检测到全身异常。该患者正在接受保守治疗,六个月来新生血管未出现进展迹象。

结论及重要性

这是首例报道的在健康患者中发生的孤立性特发性晶状体后表面新生血管形成病例。尽管后囊膜未明确的破裂或未确定的睫状体炎可引发此类新生血管形成,但对囊膜活检和睫状体进行进一步的组织病理学研究可更好地洞察其发病机制。此外,考虑到该病症无症状的特点,可对这些患者进行观察和密切监测。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae64/8603014/4369ba9cfdb9/gr1.jpg

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