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本文引用的文献

1
A Novel Apoptosis-Related Gene Signature Predicts Biochemical Recurrence of Localized Prostate Cancer After Radical Prostatectomy.一种新型凋亡相关基因特征预测根治性前列腺切除术后局限性前列腺癌的生化复发。
Front Genet. 2020 Nov 30;11:586376. doi: 10.3389/fgene.2020.586376. eCollection 2020.
2
Proposed hypothesis and rationale for association between mastitis and breast cancer.关于乳腺炎与乳腺癌之间关联的提出的假设及理论依据。
Med Hypotheses. 2020 Nov;144:110057. doi: 10.1016/j.mehy.2020.110057. Epub 2020 Jun 30.
3
Artificial intelligence for breast cancer detection in mammography and digital breast tomosynthesis: State of the art.人工智能在乳腺 X 线摄影和数字乳腺断层合成中的乳腺癌检测:现状。
Semin Cancer Biol. 2021 Jul;72:214-225. doi: 10.1016/j.semcancer.2020.06.002. Epub 2020 Jun 9.
4
Artificial intelligence radiogenomics for advancing precision and effectiveness in oncologic care (Review).人工智能放射组学在肿瘤精准医疗中的应用进展(综述)。
Int J Oncol. 2020 Jul;57(1):43-53. doi: 10.3892/ijo.2020.5063. Epub 2020 May 11.
5
Machine Learning and Mechanistic Modeling for Prediction of Metastatic Relapse in Early-Stage Breast Cancer.用于预测早期乳腺癌转移复发的机器学习与机制建模
JCO Clin Cancer Inform. 2020 Mar;4:259-274. doi: 10.1200/CCI.19.00133.
6
Breast cancer statistics, 2019.乳腺癌统计数据,2019 年。
CA Cancer J Clin. 2019 Nov;69(6):438-451. doi: 10.3322/caac.21583. Epub 2019 Oct 2.
7
Machine learning methods can more efficiently predict prostate cancer compared with prostate-specific antigen density and prostate-specific antigen velocity.与前列腺特异性抗原密度和前列腺特异性抗原速率相比,机器学习方法能更有效地预测前列腺癌。
Prostate Int. 2019 Sep;7(3):114-118. doi: 10.1016/j.prnil.2019.01.001. Epub 2019 Jan 29.
8
Diagnostic value of MRI combined with ultrasound for lymph node metastasis in breast cancer: Protocol for a meta-analysis.MRI联合超声对乳腺癌淋巴结转移的诊断价值:一项Meta分析方案
Medicine (Baltimore). 2019 Jul;98(30):e16528. doi: 10.1097/MD.0000000000016528.
9
Predicting Breast Cancer by Applying Deep Learning to Linked Health Records and Mammograms.应用深度学习对健康记录和乳腺 X 光照片进行联合分析,以预测乳腺癌。
Radiology. 2019 Aug;292(2):331-342. doi: 10.1148/radiol.2019182622. Epub 2019 Jun 18.
10
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机器学习算法在乳腺癌诊断与分类中的应用

Application of Machine Learning Algorithms in Breast Cancer Diagnosis and Classification.

作者信息

Yedjou Clement G, Tchounwou Solange S, Aló Richard A, Elhag Rashid, Mochona BereKet, Latinwo Lekan

机构信息

Department of Biological Sciences, College of Science and Technology, Florida Agricultural and Mechanical University, 1610 S. Martin Luther King Blvd, Tallahassee, FL 32307, United States.

Department of Pathology and Laboratory Medicine. School of Medicine, Tulane University, 1430 Tulane Avenue, New Orleans, LA, 70112, United States.

出版信息

Int J Sci Acad Res. 2021 Jan;2(1):3081-3086. Epub 2021 Oct 30.

PMID:34825131
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8612371/
Abstract

Breast cancer continues to be the most frequent cancer in females, affecting about one in 8 women and causing the highest number of cancer-related deaths in females worldwide despite remarkable progress in early diagnosis, screening, and patient management. All breast lesions are not malignant, and all the benign lesions do not progress to cancer. However, the accuracy of diagnosis can be increased by a combination or preoperative tests such as physical examination, mammography, fine-needle aspiration cytology, and core needle biopsy. Despite some limitations, these procedures are more accurate, reliable, and acceptable, when compared with a single adopted diagnostic procedure. Recent studies have shown that breast cancer can be accurately predicted and diagnosed using machine learning (ML) technology. The objective of this study was to explore the application of ML approaches to classify breast cancer based on feature values generated from a digitized image of a fine-needle aspiration (FNA) of a breast mass. To achieve this objective, we used ML algorithms, collected a scientific dataset of 569 breast cancer patients from Kaggle (https://www.kaggle.com/uciml/breast-cancer-wisconsin-data), analyze and interpreted the data based on ten real-valued features of a breast mass FNA including the radius, texture, perimeter, area, smoothness, compactness, concavity, concave points, symmetry, and fractal dimension. Among the 569 patients tested, 63% were diagnosed with benign breast cancer and 37% were diagnosed with malignant breast cancer. Benign tumors grow slowly and do not spread while malignant tumors grow rapidly and spread to other parts of the body.

摘要

乳腺癌仍然是女性中最常见的癌症,尽管在早期诊断、筛查和患者管理方面取得了显著进展,但全球约八分之一的女性受其影响,且乳腺癌导致的女性癌症相关死亡人数最多。并非所有乳腺病变都是恶性的,也不是所有良性病变都会发展为癌症。然而,通过体格检查、乳腺X线摄影、细针穿刺细胞学检查和粗针活检等术前检查相结合,可以提高诊断的准确性。尽管存在一些局限性,但与单一采用的诊断程序相比,这些程序更准确、可靠且可接受。最近的研究表明,使用机器学习(ML)技术可以准确预测和诊断乳腺癌。本研究的目的是探索基于乳腺肿块细针穿刺(FNA)数字化图像生成的特征值,应用ML方法对乳腺癌进行分类。为实现这一目标,我们使用了ML算法,从Kaggle(https://www.kaggle.com/uciml/breast-cancer-wisconsin-data)收集了569例乳腺癌患者的科学数据集,并基于乳腺肿块FNA的十个实值特征(包括半径、纹理、周长、面积、光滑度、致密性、凹陷度、凹陷点数、对称性和分形维数)对数据进行分析和解释。在测试的569例患者中,63%被诊断为良性乳腺癌,37%被诊断为恶性乳腺癌。良性肿瘤生长缓慢且不扩散,而恶性肿瘤生长迅速并扩散到身体其他部位。