Key Laboratory of Molecular Epidemiology of Hunan Province, School of Medicine, Hunan Normal University, Changsha, PR China.
Department of Occupational Health, Changsha Center for Disease Control and Prevention, Changsha, PR China.
Am J Ind Med. 2022 Feb;65(2):149-154. doi: 10.1002/ajim.23315. Epub 2021 Nov 25.
Workers in fireworks production are mainly at risk for explosion injury. However, there are few reports on the consequences of methanol poisoning in fireworks laborers.
We report on three patients with visual loss caused by inhalation exposure to high concentrations of methanol, who were engaged in the granulation process of the fireworks manufacturing industry. They presented with severe metabolic acidosis and visual impairments, accompanied by headache, chest tightness, shortness of breath, dizziness, and vomiting. All were diagnosed with acute methanol poisoning. One patient developed bilateral blindness and two patients improved after timely hemodialysis treatment.
These case reports emphasize the risk of methanol poisoning in the fireworks industry or other factories using commercial alcohol with high methanol content. Early hemodialysis intervention and metabolic acidosis correction are crucial for rescuing visual impairment caused by methanol exposure. Awareness and supervision of commercial alcohol use are indispensable for similar industrial processes.
烟花生产工人主要面临爆炸伤的风险。然而，关于烟花工人甲醇中毒后果的报道很少。
我们报告了 3 名因吸入高浓度甲醇而导致视力丧失的患者，他们从事烟花制造业的造粒过程。他们表现出严重的代谢性酸中毒和视力障碍，伴有头痛、胸闷、呼吸急促、头晕和呕吐。所有患者均被诊断为急性甲醇中毒。1 名患者出现双眼失明，2 名患者经及时血液透析治疗后好转。
这些病例报告强调了烟花行业或其他使用高甲醇含量商业酒精的工厂存在甲醇中毒的风险。早期血液透析干预和代谢性酸中毒纠正对视甲醇暴露引起的视力损害至关重要。对类似工业过程中商业酒精使用的认识和监督是必不可少的。
