Department of Nutrition and Dietetics, Faculty of Health Sciences, Ankara University, Ankara, Türkiye -
Department of Nutrition and Dietetics, Faculty of Health Sciences, Ankara University, Ankara, Türkiye.
Minerva Endocrinol (Torino). 2023 Sep;48(3):334-345. doi: 10.23736/S2724-6507.21.03596-X. Epub 2021 Nov 26.
Overweight and obesity are an important public health problem that affects a significant part of the world population and increases the risk of many metabolic diseases. Weight loss is the primary goal in obesity treatment, and many different dietary interventions are tried for this purpose. Intermittent fasting is a diet that has become popular in recent years with the weight loss it provides and includes periods of fasting and feeding. In addition to providing weight loss, intermittent fasting also has positive effects on important risk factors such as glucoregulatory parameters, blood lipids, and oxidative stress. Intermittent fasting appears to be an effective and safe way to achieve weight loss in obesity. It could also have therapeutic effects on obesity-related diseases. The aim of this review was to bring together up-to-date information on the effects of intermittent fasting on obesity and various obesity-related diseases, mechanisms of action, possible benefits and harms, and potential uses.
超重和肥胖是一个重要的公共卫生问题,影响了世界上很大一部分人口,并增加了许多代谢性疾病的风险。减肥是肥胖治疗的主要目标,为此尝试了许多不同的饮食干预措施。间歇性禁食是一种近年来流行的饮食方式,它可以提供减肥效果,包括禁食和进食期。间歇性禁食除了提供减肥效果外,还对葡萄糖调节参数、血脂和氧化应激等重要风险因素有积极影响。间歇性禁食似乎是一种有效和安全的减肥方法,可以用于肥胖症。它还可能对肥胖相关疾病具有治疗作用。本综述的目的是汇集关于间歇性禁食对肥胖和各种肥胖相关疾病的影响、作用机制、可能的益处和危害以及潜在用途的最新信息。