de Albuquerque Britto Diana Babini Lapa, das Chagas Angelo Mendes Tenorio Fernanda, Tenorio Bruno, Rolim Larissa, Júnior Valdemiro Silva
RENORBIO, Federal Rural University of Pernambuco - UFRPE-Recife/PE, Brazil.
Federal University of Pernambuco - UFPE-Recife/PE, Brazil.
Recent Pat Biotechnol. 2021;15(3):184-194. doi: 10.2174/1872208315666210719110606.
Plants of the genus Cannabis have been gaining attention in medicine. The most outstanding treatments include antispasmodic, analgesic, antiemetic, neuroprotective and anti-inflammatory actions. The aim of the study was to describe patents associated with cannabis and cannabinoids as a treatment for pregnant women. A search was carried out on four patent bases: National Institute of Industrial Property, Latipat, Espacenet and Patentscope. The used search keys were "Cannabis", "Cannabidiol", "Cannabinoids", "CBD" and "THC" associated with "pregnant women". Patents in any language and year were considered. A total of 1,402 patents were found in all the used databases. After reading the title and abstract, patents were excluded if they did not meet the eligibility criteria and/or if they were duplicates, thus leaving 11 patents on the use of cannabis and/or cannabinoids as treatment in pregnant women. A critical analysis was carried out. All selected patents were from the Asian continent (China), focusing on traditional Chinese medicine for treating various possible changes during pregnancy and also for diseases prevention in the postpartum period. It was found that the main causes for the need of such treatments were related to spleen deficiencies, inability and/or moisture stagnation. Finally, the vast majority of treatments used Cannabis fruits associated with other plants. Given the above, patents related to cannabis and cannabinoids for the treatment of pregnant women in the peri and postnatal periods were found to be associated with traditional Chinese medicine.
大麻属植物在医学领域正日益受到关注。最显著的治疗作用包括解痉、止痛、止吐、神经保护和抗炎作用。本研究的目的是描述与大麻和大麻素作为孕妇治疗方法相关的专利。在四个专利库进行了检索：国家工业产权局、拉丁专利局、欧洲专利局专利数据库和专利合作条约国际专利检索数据库。使用的检索关键词是与“孕妇”相关的“大麻”“大麻二酚”“大麻素”“CBD”和“THC”。考虑任何语言和年份的专利。在所有使用的数据库中总共发现了1402项专利。阅读标题和摘要后，不符合入选标准和/或为重复的专利被排除，因此剩下11项关于使用大麻和/或大麻素治疗孕妇的专利。进行了批判性分析。所有选定的专利均来自亚洲大陆（中国），重点是用于治疗孕期各种可能变化以及产后疾病预防的传统中药。发现需要此类治疗的主要原因与脾虚、无力和/或湿气停滞有关。最后，绝大多数治疗使用了与其他植物相关的大麻果实。综上所述，发现与大麻和大麻素用于围产期和产后孕妇治疗相关的专利与传统中药有关。
