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癌症治疗专利的描述性综述。

A Descriptive Review of Patents for Cancer Treatment.

机构信息

Faculty of Pharmacy, Federal University of Bahia, Campus Ondina, Salvador, BA, Brazil.

Postgraduate Program in Pharmaceutical Sciences, Federal University of Sergipe, São Cristóvão, Sergipe, Brazil.

出版信息

Recent Pat Anticancer Drug Discov. 2024;19(2):137-145. doi: 10.2174/1574892818666230213095717.

DOI:10.2174/1574892818666230213095717
PMID:36788702
Abstract

BACKGROUND

use for tumor treatment has been explored in several areas, and its potential for tumor remission is currently being studied after the discovery of the endogenous cannabinoid.

OBJECTIVE

The study aimed to conduct a critical patent review to identify and explore the latest advances and therapeutic strategies using to treat cancer.

METHODS

The research was carried out in the free and online database Espacenet, using the descriptors "cancer" and " or cannabidiol" in the title or abstract. A total of 95 patents were identified for preliminary evaluation in the database. Six duplicate patents were excluded, 12 referring to traditional Chinese medicine and 36 with a title in disagreement with the scope of this review. In addition the final selection involved 21 patents that were in line with the objective of the study.

RESULTS

As observed in the reading of patents, the interest of pharmaceutical industries and researchers and the development of new products to fight cancer have increased in recent years. The main cannabinoids present in the patents are tetrahydrocannabinol, cannabidiol, and hemp. Moreover, the patents were classified and the main applicant countries were the United States followed by Japan, with a higher filing rate in 2019 and, mainly by the industry.

CONCLUSION

In conclusion we can say that, the importance of parliamentary approval in the cultivation and investments that, in addition to bringing innovation to the industrial sector, enriches research in the area, contributing to the creation of new medicines.

摘要

背景

在发现内源性大麻素后,人们已经在多个领域探索了大麻二酚的肿瘤治疗用途,其肿瘤缓解潜力目前正在研究中。

目的

本研究旨在进行批判性专利审查,以确定和探讨使用大麻二酚治疗癌症的最新进展和治疗策略。

方法

在免费的在线数据库 Espacenet 中,使用标题或摘要中的“癌症”和“或大麻二酚”这两个词进行研究。在数据库中初步评估确定了 95 项专利。排除了 6 项重复专利,12 项涉及中药,36 项标题与本综述范围不符。此外,最终选择了 21 项符合研究目的的专利。

结果

从专利阅读中可以看出,近年来,制药行业和研究人员的兴趣以及抗癌新产品的开发有所增加。专利中主要存在的大麻素是四氢大麻酚、大麻二酚和大麻。此外,对专利进行了分类,主要申请人国家是美国,其次是日本,2019 年的申请率较高,主要由工业界提出。

结论

总之,我们可以说,议会批准在种植和投资方面的重要性,除了为工业部门带来创新外,还丰富了该领域的研究,有助于创造新的药物。

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