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用于治疗上颌低度恶性肿瘤的颧种植体穿孔(ZIP)皮瓣重建技术——35例连续治疗患者的临床及患者相关结局

The Zygomatic Implant Perforated (ZIP) flap reconstructive technique for the management of low-level maxillary malignancy - clinical & patient related outcomes on 35 consecutively treated patients.

作者信息

Butterworth Chris J, Lowe Derek, Rogers Simon N

机构信息

Department of Oral and Maxillofacial Surgery, Liverpool University Hospital Foundation Trust, Liverpool, UK.

Department of Clinical and Molecular Cancer Medicine, University of Liverpool, Liverpool, UK.

出版信息

Head Neck. 2022 Feb;44(2):345-358. doi: 10.1002/hed.26933. Epub 2021 Nov 26.

DOI:10.1002/hed.26933
PMID:34825746
Abstract

BACKGROUND

The zygomatic implant perforated (ZIP) flap technique provides immediate reconstruction and rapid dental rehabilitation for low-level malignant tumors.

METHODS

Patients who underwent ZIP flap reconstruction between December 2015 and February 2021 were followed prospectively.

RESULTS

Thirty-five consecutively treated patients were studied with 16 undergoing surgery alone and 19 undergoing surgery followed by radiotherapy. The median time to fit the prosthesis was 29 days with all patients requiring adjuvant radiotherapy receiving their fixed dental prosthesis prior to its commencement. Vascularized flap (100%), zygomatic implant (98.4%), and prosthesis (97%) survival were excellent and the ZIP flap protocol was highly rated by patient-related outcome measures especially for the chewing domain.

CONCLUSIONS

The ZIP flap technique provides an excellent means of providing an autogenous oronasal seal and a foundation for immediate cortically anchored fixed dental rehabilitation.

CLINICAL SIGNIFICANCE

This technique provides rapid and robust rehabilitation for patients presenting with low-level maxillary malignancy despite the use of radiotherapy.

摘要

背景

颧种植体穿通(ZIP)皮瓣技术可为低级别恶性肿瘤提供即刻重建和快速牙齿修复。

方法

对2015年12月至2021年2月期间接受ZIP皮瓣重建的患者进行前瞻性随访。

结果

对35例连续接受治疗的患者进行了研究,其中16例仅接受手术,19例接受手术加放疗。安装假体的中位时间为29天,所有需要辅助放疗的患者在放疗开始前均已安装固定假牙。带血管蒂皮瓣(100%)、颧种植体(98.4%)和假体(97%)的存活率很高,ZIP皮瓣方案在患者相关结局指标中获得高度评价,尤其是在咀嚼方面。

结论

ZIP皮瓣技术是提供自体口鼻封闭以及即刻皮质锚固固定牙齿修复基础的极佳方法。

临床意义

尽管使用了放疗,但该技术仍可为患有低级别上颌恶性肿瘤的患者提供快速而可靠的修复。

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J Clin Med. 2025 May 8;14(10):3278. doi: 10.3390/jcm14103278.
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Long-term treatment outcomes with zygomatic implants: a systematic review and meta-analysis.颧骨种植体的长期治疗效果:系统评价和荟萃分析。
Int J Implant Dent. 2023 Jul 5;9(1):21. doi: 10.1186/s40729-023-00479-x.
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Indications for zygomatic implants: a systematic review.颧骨种植体的适应证:系统评价。
Int J Implant Dent. 2023 Jul 1;9(1):17. doi: 10.1186/s40729-023-00480-4.
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Guided Zygomatic Implantology for Oral Cancer Rehabilitation: A Case Report.口腔癌康复的引导式颧骨种植术:一例报告
J Clin Med. 2023 May 24;12(11):3653. doi: 10.3390/jcm12113653.
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Changing trends in the microvascular reconstruction and oral rehabilitation following maxillary cancer.上颌骨癌术后的微血管重建和口腔修复的变化趋势。
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