Department of Obstetrics and Gynecology, Kanuni Sultan Suleyman Research and Training Hospital, Istanbul, Turkey.
Department of Perinatology, İstanbul University Cerrahpaşa Medical Faculty, Istanbul, Turkey.
Arch Gynecol Obstet. 2022 Sep;306(3):735-743. doi: 10.1007/s00404-021-06334-x. Epub 2021 Nov 26.
The aim of our study was to investigate the normal cortical sulcus development in fetuses without central nervous system abnormality with transabdominal ultrasonography.
Our study was planned as a cross-sectional study in our clinic between November 2011 and October 2012. The study group was selected among pregnant women who applied to our hospital for routine antenatal follow-up. Singleton pregnancies, between 15th and 32nd gestational weeks, were included in the study. During the routine fetal ultrasonographic examination of these pregnant women, sylvian sulcus, parietooccipital sulcus, calcarine sulcus, and cingulate sulcus length measurements were taken and the correlation of these values with gestational week was evaluated.
Three hundred and thirty-two patients were included in the study. Sylvian sulcus length, parietooccipital sulcus length, calcarine sulcus length, and cingulate sulcus length could be first measured respectively, at 15th, 17th, 17th and 25th gestational week. We found a positive correlation between gestational age and sylvian sulcus, parietooccipital sulcus, calcarine sulcus, and cingulate sulcus length measurements (p < 0.001).
Sulcal development and cortical maturation can be evaluated prenatally with transabdominal ultrasonography of the central nervous system.
本研究旨在通过经腹超声检查，研究无脑神经系统异常的胎儿正常皮质沟的发育情况。
本研究为 2011 年 11 月至 2012 年 10 月在我院进行的一项横断面研究。研究组选自因常规产前检查就诊于我院的孕妇。纳入本研究的孕妇均为单胎妊娠，妊娠 15-32 周。对这些孕妇进行常规胎儿超声检查时，测量外侧裂、顶枕沟、距状裂和扣带回的长度，并评估这些值与妊娠周数的相关性。
本研究共纳入 332 例患者。外侧裂长度、顶枕沟长度、距状裂长度和扣带回长度可分别在妊娠第 15、17、17 和 25 周测量。我们发现，外侧裂、顶枕沟、距状裂和扣带回长度的测量值与胎龄之间存在正相关（p<0.001）。
通过经腹超声检查中枢神经系统，可对脑沟发育和皮质成熟情况进行产前评估。
