Faculdade de Medicina Veterinária e Zootecnia, Departamento de Higiene Veterinária e Saúde Pública, Universidade Estadual Paulista "Júlio de Mesquita Filho", Botucatu, São Paulo 18618-970, Brazil.
Setor de Patologia Veterinária, Departamento de Patologia Clínica Veterinária, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil.
Acta Trop. 2022 Mar;227:106258. doi: 10.1016/j.actatropica.2021.106258. Epub 2021 Nov 23.
In the past decade, cases of Q fever have been reported in Brazil. Although the previous report of Coxiella burnetii in humans and animals, the knowledge about the occurrence of this pathogen in livestock in Brazil is scarce. This study aimed to search C. burnetii and possible coinfections in tissues of aborted bovine fetuses from Brazil. Tissue samples from seventy-six aborted bovine fetuses sent to the laboratory of molecular diagnosis of infectious diseases from 2013 to 2019 were evaluated by real-time PCR for C. burnetii. Overall, 9.2% (7/76) of the samples were positive for C. burnetii. Moreover, the molecular diagnostic history of our lab revealed the coinfection with Neospora spp. in three fetuses and the presence of histopathological features suggestive with fetal neosporosis in another one. The previous report of C. burnetii in humans and animals in the country, with the detection of C. burnetii from tissues of aborted bovine fetuses reported here, reinforces the neglected state of the disease in Brazil and raises the question of the role of the pathogen in reproductive disorders in national livestock.
在过去的十年中，巴西报告了 Q 热病例。尽管之前有关于人类和动物中贝氏柯克斯体的报告，但对巴西家畜中这种病原体的发生情况知之甚少。本研究旨在检测巴西流产牛胎儿组织中的贝氏柯克斯体和可能的合并感染。对 2013 年至 2019 年送到传染病分子诊断实验室的 76 例流产牛胎儿的组织样本进行了实时 PCR 检测，以确定是否存在贝氏柯克斯体。总体而言，9.2%（7/76）的样本为贝氏柯克斯体阳性。此外，我们实验室的分子诊断史显示，三例胎儿存在与新孢子虫属的合并感染，另一例胎儿存在疑似胎儿新孢子虫病的组织病理学特征。此前有关于该国人类和动物中贝氏柯克斯体的报告，以及这里报告的流产牛胎儿组织中贝氏柯克斯体的检出，这都表明巴西对该病的重视程度不够，并提出了该病原体在国家牲畜生殖障碍中的作用问题。
