Graduate College of Cell and Molecular Biology, Federal University of Paraná (UFPR), Curitiba, PR, 80035-050, Brazil.
Department of Animal Production and Preventive Veterinary Medicine, School of Veterinary Medicine and Animals Science, São Paulo State University, Botucatu, SP, 18618-681, Brazil.
Sci Rep. 2024 May 2;14(1):10142. doi: 10.1038/s41598-024-60850-9.
Indigenous health has posted complex challenges worldwide, particularly due to historical economic, territorial, social and environmental processes, which may lead to emergence and reemergence of pathogens. In addition to few Coxiella burnetii serosurveys in vulnerable populations, especially in developing tropical countries, no comprehensive One Health approach has focused on human-animal infection along with potential environmental determinants. Accordingly, this study aimed to assess the seroprevalence of anti-C. burnetii antibodies in indigenous populations and their dogs from 10 indigenous communities distributed in southern and southeastern Brazil, along with the correspondent healthcare professionals. In overall, 8/893 (0.90%; 95% CI 0.45-1.76) indigenous and 1/406 (0.25%) dog samples were seropositive, with 7/343 (2.04%) individuals the 1/144 (0.69%) dog from the Ocoy community, located in the city of São Miguel do Iguaçu, bordering Argentina at south, and far 10 km at west from Paraguay. All 84 healthcare professionals tested seronegative.
土著健康在全球范围内带来了复杂的挑战，特别是由于历史上的经济、领土、社会和环境进程，这可能导致病原体的出现和再现。除了脆弱人群中少数考克斯氏体血清学调查，特别是在发展中热带国家，没有全面的“同一健康”方法关注人与动物的感染以及潜在的环境决定因素。因此，本研究旨在评估巴西南部和东南部 10 个土著社区的土著居民及其狗的抗考克斯氏体抗体血清阳性率，以及相应的医疗保健专业人员。总体而言，8/893（0.90%；95%CI 0.45-1.76）名土著居民和 1/406（0.25%）名狗样本呈血清阳性，其中 Ocoy 社区的 7/343（2.04%）名个体和 1/144（0.69%）名狗来自与阿根廷接壤的圣米格尔伊瓜苏市，位于南部边境，距离巴拉圭西部 10 公里。所有 84 名医疗保健专业人员的检测结果均为血清阴性。
