Duque-Ossa L C, García-Ferrera B, Reyes-Retana J A
Tecnologico de Monterrey, Department of Mechanics and Advanced Materials, Campus Santa Fe And Estado de Mexico, Mexico.
Tecnologico de Monterrey, Department of Mechanics and Advanced Materials, Campus Santa Fe And Estado de Mexico, Mexico.
Curr Probl Cardiol. 2023 May;48(5):101067. doi: 10.1016/j.cpcardiol.2021.101067. Epub 2021 Nov 23.
Acute myocardial infarction (AMI) as the main cause of death among cardiovascular diseases is defined as a deficiency of oxygen that generates irreversible tissue necrosis in the heart muscle. For diagnostic measurements, the evaluation of cardiac markers concentration like cardiac triponin I (cTnI) in plasma or saliva thought the use of biosensors has become one of the most commonly applied strategies for prognosis of AMI. Inside this diagnostic devices, electrochemical (ECL) ones have been highly encourage to improve sensing capabilities by using different materials and configurations. In this review, the authors presents a summary of studies that involves cTnI detection using ECL biosensors modified with nanomaterials and related mechanisms.
急性心肌梗死（AMI）作为心血管疾病中的主要死亡原因，被定义为一种导致心肌出现不可逆组织坏死的缺氧状态。在诊断检测方面，通过生物传感器来评估血浆或唾液中心肌肌钙蛋白I（cTnI）等心脏标志物的浓度，已成为急性心肌梗死预后最常用的策略之一。在这类诊断设备中，电化学发光（ECL）设备因使用不同材料和配置来提高传感能力而备受推崇。在这篇综述中，作者总结了涉及使用纳米材料修饰的ECL生物传感器检测cTnI的研究及相关机制。
