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腔隙性卒中的患病率及临床特征:一项基于医院的研究。

Prevalence and Clinical Characteristics of Lacunar Stroke: A Hospital-Based Study.

作者信息

Aldriweesh Mohammed A, Alluhidan Waleed A, Al Bdah Bayan A, Alhasson Muath A, Alsaif Sultan A, Alajlani Abrar A, Almutairi Faisal M, Alskaini Mohammed A, Alotaibi Naser, Al Khathaami Ali M

机构信息

College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Riyadh 14611, Saudi Arabia.

King Abdullah International Medical Research Center, Riyadh 11481, Saudi Arabia.

出版信息

Brain Sci. 2021 Nov 5;11(11):1466. doi: 10.3390/brainsci11111466.

Abstract

Lacunar stroke (LS) is responsible for one-quarter of the overall number of ischemic strokes with long-term complications and carries health and economic issues for patients and health care systems. Therefore, we aimed to investigate lacunar versus non-lacunar strokes in a tertiary academic center. From February 2016 to July 2019, all patients admitted to the stroke unit were retrospectively reviewed. We included LS patients and compared them to other TOAST subtypes. Hemorrhagic stroke and conditions mimicking stroke were excluded. Regression analysis was done to determine LS predictors and outcomes. A 35.5% rate of LS among 989 ischemic stroke patients was found. Most patients (71.9%) were males. Lower National Institutes of Health Stroke Scale (NIHSS) scores at admission and negative history for cardiac diseases were predictors for LS in our population. At discharge, LS patients had low NIHSS scores and shorter hospitalization periods compared to non-LS patients. In conclusion, LS was prevalent among ischemic stroke patients in our cohort. Future studies are highly needed with long follow-up intervals to identify the stroke recurrence, complications, and outcomes.

摘要

腔隙性卒中(LS)占缺血性卒中总数的四分之一,会引发长期并发症,给患者及医疗保健系统带来健康和经济问题。因此,我们旨在一所三级学术中心对腔隙性卒中和非腔隙性卒中进行调查。2016年2月至2019年7月,对入住卒中单元的所有患者进行回顾性分析。我们纳入了腔隙性卒中患者,并将他们与其他TOAST亚型进行比较。排除出血性卒中和疑似卒中的情况。进行回归分析以确定腔隙性卒中的预测因素和预后。在989例缺血性卒中患者中,腔隙性卒中的发生率为35.5%。大多数患者(71.9%)为男性。入院时较低的美国国立卫生研究院卒中量表(NIHSS)评分以及无心脏病史是我们研究人群中腔隙性卒中的预测因素。出院时,与非腔隙性卒中患者相比,腔隙性卒中患者的NIHSS评分较低,住院时间较短。总之,在我们的队列中,腔隙性卒中在缺血性卒中患者中很常见。非常需要开展长期随访的进一步研究,以确定卒中复发、并发症及预后情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/88c9/8615713/7ec1de324248/brainsci-11-01466-g001.jpg

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