Department of Pediatric Cardiology and Cardiac Surgery, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.
Genetics and Rare Diseases Research Division, Ospedale Pediatrico Bambino Gesù, IRCCS, 00165 Rome, Italy.
Genes (Basel). 2021 Nov 10;12(11):1782. doi: 10.3390/genes12111782.
Pericarditis with pericardial effusion in SARS CoV-2 infection is a well-known entity in adults. In children and adolescents, only a few cases have been reported. Here, we present here a case of a 15-year-old girl affected by Sotos syndrome with pre-tamponed pericardial effusion occurred during SARS-CoV-2 infection. A possible relation between SARS-CoV-2 pericarditis and genetic syndromes, as a major risk factor for the development of severe inflammation, has been speculated. We emphasize the importance of active surveillance by echocardiograms when SARS-CoV-2 infection occurs in combination with a genetic condition.
在 SARS-CoV-2 感染中，合并心包积液的心包炎在成人中是一种众所周知的病症。在儿童和青少年中，仅有少数病例报道。在此，我们报告了一例患有 Sotos 综合征的 15 岁女孩，在 SARS-CoV-2 感染期间发生了预填塞的心包积液。有人推测，SARS-CoV-2 心包炎与遗传综合征之间可能存在关联，因为遗传综合征是引发严重炎症的一个主要危险因素。当 SARS-CoV-2 感染合并遗传疾病时，我们强调通过超声心动图进行积极监测的重要性。
