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意大利一家大学医院医护人员中与新型冠状病毒感染风险相关的因素

Factors Associated with SARS-CoV-2 Infection Risk among Healthcare Workers of an Italian University Hospital.

作者信息

Modenese Alberto, Casolari Loretta, Rossi Giorgia, Della Vecchia Elena, Glieca Francesca, D'Elia Cristiana, Garavini Denise, Righi Elena, Mariani Stefania, Venturelli Luca, Vivoli Daniela, Gobba Fabriziomaria

机构信息

Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy.

Health Surveillance Service, University Hospital of Modena, 41125 Modena, Italy.

出版信息

Healthcare (Basel). 2021 Nov 2;9(11):1495. doi: 10.3390/healthcare9111495.

DOI:10.3390/healthcare9111495
PMID:34828540
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8622462/
Abstract

We report the results of a study on the cumulative incidence of SARS-CoV-2 infections in about 6000 workers of the University Hospital of Modena, Northern Italy, in the period March 2020-January 2021, and the relations with some individual and occupational factors. Overall, in healthcare workers (HCW) the cumulative incidence of COVID-19 during the period was 13.8%. Results confirm the role of overweight and obesity as significant risk factors for SARS-CoV-2 infection. Chronic respiratory diseases, including asthma, also proved to be significantly associated with the infection rate. Considering occupational factors, the COVID-19 risk was about threefold (OR: 2.7; 95% CI 1.7-4.5) greater in nurses and nurse aides than in non-HCW, and about double (OR: 1.9; 95% CI 1.2-3.2) in physicians. Interestingly, an association was also observed between infection risk and nightshifts at work (OR: 1.8; 95% CI 1.4-2.3), significantly related to the total number of shifts in the whole eleven-month period. Even if the vaccination campaign has now greatly modified the scenario of SARS-CoV-2 infections among HCW, the results of this study can be useful for further development of health and policy strategies to mitigate the occupational risk related to the new variants of coronavirus, and therefore the evolution of the pandemic.

摘要

我们报告了一项关于意大利北部摩德纳大学医院约6000名工作人员在2020年3月至2021年1月期间感染SARS-CoV-2的累积发病率及其与一些个人和职业因素关系的研究结果。总体而言,在此期间医护人员(HCW)中COVID-19的累积发病率为13.8%。结果证实超重和肥胖是SARS-CoV-2感染的重要危险因素。包括哮喘在内的慢性呼吸道疾病也被证明与感染率显著相关。考虑职业因素,护士和护理助理感染COVID-19的风险比非医护人员高约三倍(OR:2.7;95%CI 1.7 - 4.5),医生的风险约为两倍(OR:1.9;95%CI 1.2 - 3.2)。有趣的是,还观察到感染风险与夜班工作之间存在关联(OR:1.8;95%CI 1.4 - 2.3),这与整个十一个月期间的总轮班次数显著相关。即使疫苗接种运动现在已极大地改变了医护人员中SARS-CoV-2感染的情况,但本研究结果对于进一步制定健康和政策策略以减轻与新冠病毒新变种相关的职业风险以及大流行的演变仍可能有用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7b27/8622462/fc786bc6c0ac/healthcare-09-01495-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7b27/8622462/fc786bc6c0ac/healthcare-09-01495-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7b27/8622462/fc786bc6c0ac/healthcare-09-01495-g001.jpg

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