Tieppo Francio Vincius, Gill Benjamin, Rupp Adam, Sack Andrew, Sayed Dawood
Department of Rehabilitation Medicine, The University of Kansas Medical Center (KUMC), Kansas City, KS 66160, USA.
Department of Physical Medicine and Rehabilitation, The University of Missouri, Columbia, MO 65212, USA.
Healthcare (Basel). 2021 Nov 15;9(11):1554. doi: 10.3390/healthcare9111554.
Low back pain is consistently documented as the most expensive and leading cause of disability. The majority of cases have non-specific etiologies. However, a subset of vertebral diseases has well-documented pain generators, including vertebral body tumors, vertebral body fractures, and vertebral endplate injury. Over the past two decades, specific interventional procedures targeting these anatomical pain generators have been widely studied, including spinal tumor ablation, vertebral augmentation, and basivertebral nerve ablation. This scoping review summarizes safety and clinical efficacy and discusses the impact on healthcare utilization of these interventions. Vertebral-related diseases remain a top concern with regard to prevalence and amount of health care spending worldwide. Our study shows that for a subset of disorders related to the vertebrae, spinal tumor ablation, vertebral augmentation, and basivertebral nerve ablation are safe and clinically effective interventions to decrease pain, improve function and quality of life, and potentially reduce mortality, improve survival, and overall offer cost-saving opportunities.
下背痛一直被记录为最昂贵且导致残疾的主要原因。大多数病例病因不明。然而，一部分脊柱疾病有明确记录的疼痛根源，包括椎体肿瘤、椎体骨折和椎体终板损伤。在过去二十年中，针对这些解剖学疼痛根源的特定介入手术得到了广泛研究，包括脊柱肿瘤消融、椎体强化和椎基底神经消融。本综述总结了这些干预措施的安全性和临床疗效，并讨论了其对医疗保健利用的影响。脊柱相关疾病在全球范围内的患病率和医疗支出方面仍然是首要关注点。我们的研究表明，对于一部分与椎体相关的疾病，脊柱肿瘤消融、椎体强化和椎基底神经消融是安全且临床有效的干预措施，可减轻疼痛、改善功能和生活质量，并有可能降低死亡率、提高生存率，总体上提供节省成本的机会。
