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65岁及以上社区居住女性睡眠质量、焦虑和抑郁与认知及执行功能的关联:一项横断面研究。

Associations of Sleep Quality, Anxiety, and Depression with Cognitive and Executive Functions among Community-Dwelling Women Aged ≥ 65 Years: A Cross-Sectional Study.

作者信息

Parra-Díaz Ana Belén, Aibar-Almazán Agustín, Martínez-Amat Antonio, Jiménez-García José Daniel, Álvarez-Salvago Francisco, Hita-Contreras Fidel

机构信息

Department of Health Sciences, Faculty of Health Sciences, University of Jaén, 23071 Jaén, Spain.

Department of Physiotherapy, Faculty of Health Sciences, European University of Valencia, 46112 Valencia, Spain.

出版信息

Healthcare (Basel). 2021 Nov 21;9(11):1599. doi: 10.3390/healthcare9111599.

Abstract

(1) Background: The objective of this study was to evaluate the associations of sleep quality, anxiety, and depression with cognitive performance, executive functions, and verbal fluency among women aged ≥ 65 years; (2) Methods: A cross-sectional study was conducted on 241 women (72.52 ± 3.93 years). Cognitive performance (Mini-Mental State Examination) and impairment (Montreal Cognitive Assessment), verbal fluency (Isaacs test) and executive function (Trail Making Test), Sleep quality (Pittsburgh Sleep quality Index) and anxiety and depression (Hospital Anxiety and Depression Scale) were determined; (3) Results: The linear regression analysis indicated that anxiety, depression and age, were related to lower Mini-Mental State Examination score (adjusted R = 0.306), and age, anxiety and daytime dysfunction were linked to reduced Montreal Cognitive Assessment score (adjusted R = 0.248). Age and daytime dysfunction were associated with worse verbal fluency (adjusted R = 0.094). Finally, sleep latency, sleep disturbances, the Pittsburgh Sleep quality Index total score were associated with longer times in TMT-A (adjusted R = 0.758) and TMT-B (adjusted R = 0.508); (4) Conclusions: Sleep quality was associated with cognitive performance, verbal fluency and executive functions. Besides, both anxiety and depression were related with cognitive performance, while only anxiety was linked to executive functions. As for confounders, age was associated with cognitive performance and verbal fluency.

摘要

(1) 背景:本研究的目的是评估65岁及以上女性的睡眠质量、焦虑和抑郁与认知能力、执行功能及语言流畅性之间的关联;(2) 方法:对241名女性(72.52 ± 3.93岁)进行了一项横断面研究。测定了认知能力(简易精神状态检查表)和损伤情况(蒙特利尔认知评估)、语言流畅性(艾萨克斯测试)和执行功能(连线测验)、睡眠质量(匹兹堡睡眠质量指数)以及焦虑和抑郁(医院焦虑抑郁量表);(3) 结果:线性回归分析表明,焦虑、抑郁和年龄与较低的简易精神状态检查表得分相关(调整后R = 0.306),年龄、焦虑和日间功能障碍与较低的蒙特利尔认知评估得分相关(调整后R = 0.248)。年龄和日间功能障碍与较差的语言流畅性相关(调整后R = 0.094)。最后,睡眠潜伏期、睡眠障碍、匹兹堡睡眠质量指数总分与连线测验A部分(调整后R = 0.758)和B部分(调整后R = 0.508)的较长时间相关;(4) 结论:睡眠质量与认知能力、语言流畅性和执行功能相关。此外,焦虑和抑郁均与认知能力相关,而只有焦虑与执行功能相关。至于混杂因素,年龄与认知能力和语言流畅性相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/53bc/8623846/b174d74f95fa/healthcare-09-01599-g001.jpg

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