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体育与血友病患儿:当前趋势

Sports and Children with Hemophilia: Current Trends.

作者信息

Moretti Lorenzo, Bizzoca Davide, Buono Claudio, Ladogana Teresa, Albano Federica, Moretti Biagio

机构信息

Orthopaedics Unit, Department of Basic Medical Science, Neuroscience and Sensory Organs, School of Medicine, University of Bari "Aldo Moro", AOU Consorziale Policlinico, 70124 Bari, Italy.

PhD Course in Public Health, Clinical Medicine and Oncology, University of Bari "Aldo Moro", Piazza Giulio Cesare 11, 70124 Bari, Italy.

出版信息

Children (Basel). 2021 Nov 19;8(11):1064. doi: 10.3390/children8111064.

DOI:10.3390/children8111064
PMID:34828778
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8625282/
Abstract

Hemophilia is a sex-linked recessive disorder characterized by a lack of blood factors necessary for clotting. This review aims to investigate the benefits of sports activities in children with hemophilia in terms of both physical and psychological wellness. Sports activity is necessary for children with hemophilia to preserve joints' range of motion, reduce joint bleeding, improve muscle mass and strength, enhance proprioception and prevent secondary chronic diseases. In the past, high-impact sports were usually forbidden in children with hemophilia because of their high bleeding risk. Recent studies, however, have shown that prophylaxis therapy can allow a hemophilic child to take part in vigorous activities or high-impact sports. The benefits of sports activity in children with hemophilia are expressed by a better muscular trophism and an improved bone mineral density. Moreover, physical activity has a positive impact on children's psychosocial well-being. Due to prophylaxis therapy, the quality of life of children with hemophilia is similar to their peers, and this has allowed an improvement in sports participation, including team sports.

摘要

血友病是一种X连锁隐性疾病,其特征是缺乏凝血所需的血液因子。本综述旨在探讨体育活动对血友病儿童身心健康的益处。体育活动对于血友病儿童保持关节活动范围、减少关节出血、增加肌肉量和力量、增强本体感觉以及预防继发性慢性病是必要的。过去,由于出血风险高,血友病儿童通常被禁止进行高强度运动。然而,最近的研究表明,预防性治疗可以让血友病儿童参与剧烈活动或高强度运动。体育活动对血友病儿童的益处表现为更好的肌肉营养状态和改善的骨密度。此外,体育活动对儿童的心理社会幸福感有积极影响。由于预防性治疗,血友病儿童的生活质量与同龄人相似,这使得包括团队运动在内的体育参与有所改善。

相似文献

1
Sports and Children with Hemophilia: Current Trends.体育与血友病患儿:当前趋势
Children (Basel). 2021 Nov 19;8(11):1064. doi: 10.3390/children8111064.
2
Defining the impact of hemophilia: the Academic Achievement in Children with Hemophilia Study.界定血友病的影响:血友病患儿学业成就研究
Pediatrics. 2001 Dec;108(6):E105. doi: 10.1542/peds.108.6.e105.
3
Sporting Activities and Quality of Life in Children With Hemophilia: An Observational Study.血友病患儿的体育活动与生活质量:一项观察性研究。
Pediatr Phys Ther. 2016 winter;28(4):453-9. doi: 10.1097/PEP.0000000000000296.
4
Athletic participation in severe hemophilia: bleeding and joint outcomes in children on prophylaxis.重度血友病患者的运动参与情况:接受预防治疗儿童的出血及关节情况
Pediatrics. 2009 Nov;124(5):1267-72. doi: 10.1542/peds.2009-0072. Epub 2009 Oct 12.
5
Participation and risk-taking behaviour in sports in children with haemophilia.儿童血友病患者的运动参与和冒险行为。
Haemophilia. 2009 May;15(3):686-94. doi: 10.1111/j.1365-2516.2009.02006.x.
6
Clotting factor concentrates given to prevent bleeding and bleeding-related complications in people with hemophilia A or B.凝血因子浓缩物用于预防甲型或乙型血友病患者的出血及与出血相关的并发症。
Cochrane Database Syst Rev. 2006 Apr 19(2):CD003429. doi: 10.1002/14651858.CD003429.pub3.
7
Clotting factor concentrates given to prevent bleeding and bleeding-related complications in people with hemophilia A or B.凝血因子浓缩物用于预防甲型或乙型血友病患者的出血及与出血相关的并发症。
Cochrane Database Syst Rev. 2005 Apr 18(2):CD003429. doi: 10.1002/14651858.CD003429.pub2.
8
Promoting Sports Practice in Persons with Hemophilia: A Survey of Clinicians' Perspective.促进血友病患者的体育锻炼:临床医生观点的调查。
Int J Environ Res Public Health. 2021 Nov 11;18(22):11841. doi: 10.3390/ijerph182211841.
9
Individualized prophylaxis for optimizing hemophilia care: can we apply this to both developed and developing nations?优化血友病护理的个体化预防措施:我们能否将其应用于发达国家和发展中国家?
Thromb J. 2016 Oct 4;14(Suppl 1):32. doi: 10.1186/s12959-016-0096-y. eCollection 2016.
10
Clotting factor concentrates given to prevent bleeding and bleeding-related complications in people with hemophilia A or B.凝血因子浓缩物用于预防甲型或乙型血友病患者的出血及与出血相关的并发症。
Cochrane Database Syst Rev. 2011 Sep 7(9):CD003429. doi: 10.1002/14651858.CD003429.pub4.

引用本文的文献

1
Risk factors for joint bleeding in severe hemophilia A and B: analysis of the Community Counts longitudinal surveillance cohort.重度甲型和乙型血友病关节出血的危险因素:社区计数纵向监测队列分析
Blood Vessel Thromb Hemost. 2025 Jan 15;2(3):100047. doi: 10.1016/j.bvth.2025.100047. eCollection 2025 Aug.
2
The effect of prophylactic FVIII infusion combined with personalized rehabilitation on joint health and quality of life in children with hemophilia.预防性输注凝血因子VIII联合个性化康复对血友病儿童关节健康和生活质量的影响。
Front Pediatr. 2025 Jul 10;13:1578617. doi: 10.3389/fped.2025.1578617. eCollection 2025.
3
Teenagers and Adolescents with Hemophilia-Need for a Specific Approach.青少年血友病患者——需要特定的治疗方法
J Clin Med. 2024 Aug 29;13(17):5121. doi: 10.3390/jcm13175121.
4
A Qualitative Study Exploring the Experiences and Perceptions of Patients with Hemophilia Regarding Their Health-Related Well-Being, in Salamanca.一项质性研究:探索萨拉曼卡血友病患者对其健康相关福祉的体验与认知
J Clin Med. 2023 Aug 21;12(16):5417. doi: 10.3390/jcm12165417.
5
Sexual activity and the adolescent with haemophilia.青少年血友病患者的性行为。
Acta Biomed. 2023 Apr 24;94(2):e2023003. doi: 10.23750/abm.v94i2.14168.
6
Bone Development and Disease in Infants.婴儿的骨骼发育与疾病
Children (Basel). 2022 Apr 6;9(4):519. doi: 10.3390/children9040519.

本文引用的文献

1
Sports participation is not associated with adherence to prophylaxis in Dutch patients with haemophilia.在荷兰血友病患者中,体育活动与预防措施的依从性无关。
Haemophilia. 2021 May;27(3):e402-e405. doi: 10.1111/hae.14244. Epub 2021 Feb 8.
2
Therapeutic value of kinesio taping in reducing lower back pain and improving back muscle endurance in adolescents with hemophilia.运动贴扎对降低血友病青少年腰痛和提高腰背肌耐力的治疗价值。
J Musculoskelet Neuronal Interact. 2020 Jun 1;20(2):256-264.
3
Establishing an online physical exercise program for people with hemophilia.为血友病患者建立在线体育锻炼项目。
Wien Klin Wochenschr. 2019 Nov;131(21-22):558-566. doi: 10.1007/s00508-019-01548-1. Epub 2019 Sep 18.
4
The Paediatric Haemophilia Activities List (pedHAL) in routine assessment: changes over time, child-parent agreement and informative domains.儿科血友病活动清单(pedHAL)在常规评估中的应用:随时间变化的变化、患儿-家长一致性和信息性领域。
Haemophilia. 2019 Nov;25(6):953-959. doi: 10.1111/hae.13835. Epub 2019 Aug 16.
5
Increasing Wellness Through Physical Activity in Children With Chronic Disease and Disability.通过体育活动提升慢性病和残疾儿童的健康水平
Curr Sports Med Rep. 2018 Dec;17(12):425-432. doi: 10.1249/JSR.0000000000000548.
6
A case of moderate haemophilia A with inhibitor, carrying the p.R1800H mutation, complicated with juvenile idiopathic arthritis.一例携带p.R1800H突变的中度甲型血友病伴抑制剂,并发幼年特发性关节炎。
Haemophilia. 2019 Jan;25(1):e51-e54. doi: 10.1111/hae.13648. Epub 2018 Dec 3.
7
Sport-Related Concussion in Children and Adolescents.儿童和青少年与运动相关的脑震荡。
Pediatrics. 2018 Dec;142(6). doi: 10.1542/peds.2018-3074. Epub 2018 Nov 12.
8
How I approach managing student athletes at risk for bleeding.我如何管理有出血风险的运动员学生。
Pediatr Blood Cancer. 2019 Feb;66(2):e27523. doi: 10.1002/pbc.27523. Epub 2018 Oct 26.
9
Male gender, school attendance and sports participation are positively associated with health-related quality of life in children and adolescents with congenital bleeding disorders.男性性别、上学和参与体育运动与患有先天性出血性疾病的儿童和青少年的健康相关生活质量呈正相关。
Haemophilia. 2018 May;24(3):395-404. doi: 10.1111/hae.13420. Epub 2018 Feb 8.
10
Measuring activities and participation in persons with haemophilia: A systematic review of commonly used instruments.测量血友病患者的活动和参与:常用工具的系统评价。
Haemophilia. 2018 Mar;24(2):e33-e49. doi: 10.1111/hae.13367. Epub 2017 Nov 27.