Ren Guixing, Fan Xin, Teng Cong, Li Yajie, Everaert Nadia, Blecker Christophe
College of Pharmacy and Biological Engineering, Chengdu University, No. 1 Shilling Road, Chenglo Avenue, Longquan District, Chengdu 610106, China.
Institute of Crop Science, Chinese Academy of Agricultural Sciences, No. 80 South Xueyuan Road, Haidian District, Beijing 100081, China.
Foods. 2021 Nov 22;10(11):2891. doi: 10.3390/foods10112891.
In recent years, chronic diseases including obesity, diabetes, cancer, cardiovascular, and neurodegenerative disorders have been the leading causes of incapacity and death globally. Increasing evidence suggests that improvements of lifestyle habits and diet is the most commonly adopted strategy for the prevention of chronic disorders. Moreover, many dietary compounds have revealed health-promoting benefits beyond their nutritional effects. It is worth noting that diet plays an important role in shaping the intestinal microbiota. Coarse cereals constitute important sources of nutrients for the gut microbiota and contribute to a healthy gut microbiome. Furthermore, the gut microbiota converts coarse cereals into functional substances and mediates the interaction between the host and these components. In this study, we summarize the recent findings concerning functional components of cereal grains and their potential chemopreventive activity via modulating the gut microbiota.
近年来，包括肥胖、糖尿病、癌症、心血管疾病和神经退行性疾病在内的慢性病已成为全球致残和死亡的主要原因。越来越多的证据表明，改善生活习惯和饮食是预防慢性疾病最常用的策略。此外，许多膳食化合物除了具有营养作用外，还显示出促进健康的益处。值得注意的是，饮食在塑造肠道微生物群方面起着重要作用。粗粮是肠道微生物群的重要营养来源，有助于形成健康的肠道微生物组。此外，肠道微生物群将粗粮转化为功能物质，并介导宿主与这些成分之间的相互作用。在本研究中，我们总结了关于谷物功能成分及其通过调节肠道微生物群发挥潜在化学预防活性的最新研究结果。
