Jang Sung-Ho, Bae Chang-Hoon, Kim Jae-Woon, Kwon Hyeok-Gyu
Department of Physical Medicine and Rehabilitation, College of Medicine, Yeungnam University, Daegu 42415, Korea.
Department of Otorhinolaryngology-Head and Neck Surgery, College of Medicine, Yeungnam University, Daegu 42415, Korea.
Diagnostics (Basel). 2021 Nov 9;11(11):2070. doi: 10.3390/diagnostics11112070.
Some studies have reported that a core vestibular projection (CVP) injury is associated with dizziness following a brain injury using diffusion tensor tractography (DTT). On the other hand, there has been no DTT study on dizziness caused by a CVP injury in patients with mild traumatic brain injury (TBI). In this study, DTT was used to examine the relationship between dizziness and CVP injury in patients with mild TBI. Forty-three patients with mild TBI and twenty-nine normal subjects were recruited. The patients were classified into two groups based on the dizziness score: group A, patients with a dizziness score less than 2 on the sub-item score for dizziness in the Rivermead Post-concussion Symptoms Questionnaire; group B, patients with a dizziness score above 2. The tract volume (TV) in group B was significantly lower than group A and the control group ( < 0.05). By contrast, the TV in group A was similar to the control group ( > 0.05). Regarding the correlation, the dizziness score of all patients showed a strong negative correlation with the TV of the CVP ( = -0.711, < 0.05). DTT revealed the CVP injury in patients with dizziness after mild TBI. In addition, the severity of dizziness of these patients was closely related to the injury severity of the CVP.
一些研究报告称，使用弥散张量纤维束成像（DTT）发现，核心前庭投射（CVP）损伤与脑损伤后的头晕有关。另一方面，尚未有关于轻度创伤性脑损伤（TBI）患者中由CVP损伤引起的头晕的DTT研究。在本研究中，使用DTT来检查轻度TBI患者头晕与CVP损伤之间的关系。招募了43例轻度TBI患者和29名正常受试者。根据头晕评分将患者分为两组：A组，Rivermead脑震荡后症状问卷中头晕子项评分低于2分的患者；B组，头晕评分高于2分的患者。B组的纤维束体积（TV）显著低于A组和对照组（<0.05）。相比之下，A组的TV与对照组相似（>0.05）。关于相关性，所有患者的头晕评分与CVP的TV呈强负相关（=-0.711，<0.05）。DTT揭示了轻度TBI后头晕患者的CVP损伤。此外，这些患者头晕的严重程度与CVP的损伤严重程度密切相关。
