植物免疫与 NPR1 代谢中 ATGs 作用的研究进展。
Research Progress of ATGs Involved in Plant Immunity and NPR1 Metabolism.
机构信息
MOE Key Laboratory of Laser Life Science, Institute of Laser Life Science, College of Biophotonics, South China Normal University, Guangzhou 510631, China.
Guangdong Provincial Key Laboratory of Laser Life Science, College of Biophotonics, South China Normal University, Guangzhou 510631, China.
出版信息
Int J Mol Sci. 2021 Nov 9;22(22):12093. doi: 10.3390/ijms222212093.
Autophagy is an important pathway of degrading excess and abnormal proteins and organelles through their engulfment into autophagosomes that subsequently fuse with the vacuole. Autophagy-related genes (ATGs) are essential for the formation of autophagosomes. To date, about 35 ATGs have been identified in , which are involved in the occurrence and regulation of autophagy. Among these, 17 proteins are related to resistance against plant pathogens. The transcription coactivator non-expressor of pathogenesis-related genes 1 (NPR1) is involved in innate immunity and acquired resistance in plants, which regulates most salicylic acid (SA)-responsive genes. This paper mainly summarizes the role of ATGs and NPR1 in plant immunity and the advancement of research on ATGs in NPR1 metabolism, providing a new idea for exploring the relationship between ATGs and NPR1.
自噬是通过将多余和异常的蛋白质和细胞器吞噬到自噬体中，然后自噬体与液泡融合，从而降解它们的重要途径。自噬相关基因（ATGs）对于自噬体的形成是必不可少的。迄今为止，在 中已经鉴定出约 35 个 ATGs，它们参与自噬的发生和调节。其中，17 种蛋白质与植物病原体的抗性有关。转录共激活因子非表达与发病相关基因 1（NPR1）与植物的先天免疫和获得性抗性有关，它调节大多数水杨酸（SA）响应基因。本文主要总结了 ATGs 和 NPR1 在植物免疫中的作用以及 ATGs 在 NPR1 代谢研究中的进展，为探索 ATGs 和 NPR1 之间的关系提供了新的思路。
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