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癌症基因组学和生物信息学工具开发的最新趋势。

Recent Trends in Cancer Genomics and Bioinformatics Tools Development.

机构信息

The Digital Health Institute, I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University), 119991 Moscow, Russia.

Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.

出版信息

Int J Mol Sci. 2021 Nov 10;22(22):12146. doi: 10.3390/ijms222212146.

DOI:10.3390/ijms222212146
PMID:34830028
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8618360/
Abstract

We overview recent research trends in cancer genomics, bioinformatics tools development and medical genetics, based on results discussed in papers collections "Medical Genetics, Genomics and Bioinformatics" (https://www [...].

摘要

我们根据“医学遗传学、基因组学和生物信息学”(https://www [...].)论文集中讨论的结果,概述癌症基因组学、生物信息学工具开发和医学遗传学的最新研究趋势。

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本文引用的文献

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Bioinformatics Applications to Reveal Molecular Mechanisms of Gene Expression Regulation in Model Organisms.生物信息学在揭示模式生物基因表达调控的分子机制中的应用。
Int J Mol Sci. 2021 Nov 5;22(21):11973. doi: 10.3390/ijms222111973.
2
Precise Characterization of Genetic Interactions in Cancer via Molecular Network Refining Processes.通过分子网络细化过程精确刻画癌症中的遗传相互作用。
Int J Mol Sci. 2021 Oct 15;22(20):11114. doi: 10.3390/ijms222011114.
3
Medical Genetics, Genomics and Bioinformatics Aid in Understanding Molecular Mechanisms of Human Diseases.医学遗传学、基因组学和生物信息学有助于理解人类疾病的分子机制。
Int J Mol Sci. 2021 Sep 15;22(18):9962. doi: 10.3390/ijms22189962.
4
Unraveling the Relevance of ARL GTPases in Cutaneous Melanoma Prognosis through Integrated Bioinformatics Analysis.通过综合生物信息学分析揭示 ARL GTPases 在皮肤黑色素瘤预后中的相关性。
Int J Mol Sci. 2021 Aug 26;22(17):9260. doi: 10.3390/ijms22179260.
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Multiple Sclerosis: Enzymatic Cross Site-Specific Hydrolysis of H1 Histone by IgGs against H1, H2A, H2B, H3, H4 Histones, and Myelin Basic Protein.多发性硬化症:针对组蛋白 H1、H2A、H2B、H3、H4 和髓鞘碱性蛋白的 IgG 对 H1 组蛋白的酶促交叉位点特异性水解。
Biomolecules. 2021 Aug 2;11(8):1140. doi: 10.3390/biom11081140.
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Hierarchical Structure of Protein Sequence.蛋白质序列的层次结构。
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