Dowgiałło-Gornowicz Natalia, Sztaba Klaudia, Lech Paweł, Botulińska Anna, Michalik Maciej
Department of General, Minimally Invasive and Elderly Surgery, University of Warmia and Mazury, 10-045 Olsztyn, Poland.
Department of Family Medicine and Infectious Disease, University of Warmia and Mazury, 10-045 Olsztyn, Poland.
Medicina (Kaunas). 2021 Nov 14;57(11):1242. doi: 10.3390/medicina57111242.
: Gastrointestinal stromal tumors (GISTs) are rare mesenchymal neoplasms located mainly in the fundus (60-70%). The incidence of GIST is approximately 10 per million population per year in Europe, with a peak incidence at the age of 63. Recent studies suggest that morbidly obese patients have a higher incidence of GIST than the general population. The aim of this study was to analyze the incidence of GIST in patients undergoing laparoscopic sleeve gastrectomy (LSG) in our department. : this paper present the retrospective study of prospectively collected data of 1564 patients who underwent LSG in a single large bariatric center from October 2013 to September 2021. After surgery, each sample of the resected stomach was sent for histopathological examination. For the analysis, we included patients diagnosed with GIST intraoperatively or postoperatively. : GISTs were found in five patients (0.31%). There were three men and two women. The mean age was 50.2 (range 32-63 ± 11.8) and the mean preoperative body mass index was 43.3 kg/m (40-49.4 ± 3.2). In four cases, GISTs were found in the fundus (80%), and in one in the pylorus (20%). None of the tumors were larger than 7 mm in diameter and all were diagnosed as a very low-risk category. No adjuvant treatment was required. All patients achieved good or satisfactory bariatric and metabolic results. : The incidence of GIST in our study was estimated at 0.31%. All patients had a very low-risk GIST and no recurrence until follow-up. Recent literature suggests that the risk of GIST is higher in the obese population, and therefore surgeons should be aware of the risk of incidental GIST during LSG.
胃肠道间质瘤（GISTs）是一种罕见的间叶组织肿瘤，主要位于胃底（60 - 70%）。在欧洲，GIST的发病率约为每年每百万人口10例，发病高峰年龄为63岁。最近的研究表明，病态肥胖患者GIST的发病率高于普通人群。本研究的目的是分析我科接受腹腔镜袖状胃切除术（LSG）患者中GIST的发病率。本文呈现了一项回顾性研究，该研究前瞻性收集了2013年10月至2021年9月在一个大型减肥中心接受LSG的1564例患者的数据。手术后，将切除胃的每个样本送去进行组织病理学检查。为进行分析，我们纳入了术中或术后被诊断为GIST的患者。在5例患者（0.31%）中发现了GIST。其中男性3例，女性2例。平均年龄为50.2岁（范围32 - 63±11.8），术前平均体重指数为43.3 kg/m²（40 - 49.4±3.2）。4例GIST位于胃底（80%），1例位于幽门（20%）。所有肿瘤直径均不超过7 mm，均被诊断为极低风险类别。无需辅助治疗。所有患者均取得了良好或满意的减肥和代谢效果。我们研究中GIST的发病率估计为0.31%。所有患者的GIST风险极低，随访期间无复发。最近的文献表明，肥胖人群中GIST的风险更高，因此外科医生在进行LSG时应意识到偶然发现GIST的风险。
