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高度区分的生理参数用于热模式分类。

Highly Discriminative Physiological Parameters for Thermal Pattern Classification.

机构信息

Computer Vision Laboratory, Universidad Politécnica de Tulancingo, Tulancingo de Bravo 43629, Mexico.

出版信息

Sensors (Basel). 2021 Nov 21;21(22):7751. doi: 10.3390/s21227751.

DOI:10.3390/s21227751
PMID:34833827
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8618047/
Abstract

Infrared Thermography (IRT) is a non-contact, non-intrusive, and non-ionizing radiation tool used for detecting breast lesions. This paper analyzes the surface temperature distribution (STD) on an optimal Region of Interest (RoI) for extraction of suitable internal heat source parameters. The physiological parameters are estimated through the inverse solution of the bio-heat equation and the STD of suspicious areas related to the hottest spots of the RoI. To reach these values, the STD is analyzed by means: the Depth-Intensity-Radius (D-I-R) measurement model and the fitting method of Lorentz curve. A highly discriminative pattern vector composed of the extracted physiological parameters is proposed to classify normal and abnormal breast thermograms. A well-defined RoI is delimited at a radial distance, determined by the Support Vector Machines (SVM). Nevertheless, this distance is less than or equal to 1.8 cm due to the maximum temperature location close to the boundary image. The methodology is applied to 87 breast thermograms that belong to the Database for Mastology Research with Infrared Image (DMR-IR). This methodology does not apply any image enhancements or normalization of input data. At an optimal position, the three-dimensional scattergrams show a correct separation between normal and abnormal thermograms. In other cases, the feature vectors are highly correlated. According to our experimental results, the proposed pattern vector extracted at optimal position a=1.6 cm reaches the highest sensitivity, specificity, and accuracy. Even more, the proposed technique utilizes a reduced number of physiological parameters to obtain a Correct Rate Classification (CRC) of 100%. The precision assessment confirms the performance superiority of the proposed method compared with other techniques for the breast thermogram classification of the DMR-IR.

摘要

红外热成像(IRT)是一种非接触、非侵入性且无电离辐射的工具,用于检测乳房病变。本文分析了最佳感兴趣区域(ROI)的表面温度分布(STD),以提取合适的内部热源参数。通过生物热方程的逆解和与 ROI 热点相关的可疑区域的 STD,估计生理参数。为了达到这些值,通过以下方法分析 STD:深度-强度-半径(D-I-R)测量模型和洛伦兹曲线拟合方法。提出了一种由提取的生理参数组成的高度区分模式向量,用于对正常和异常乳房热图进行分类。在支持向量机(SVM)的确定下,定义了一个明确的 ROI 区域,该区域的径向距离为。然而,由于最大温度位置接近边界图像,因此该距离小于或等于 1.8 厘米。该方法应用于 87 个属于乳腺红外图像研究数据库(DMR-IR)的乳房热图。该方法不应用任何图像增强或输入数据归一化。在最佳位置,三维散点图正确地区分了正常和异常热图。在其他情况下,特征向量高度相关。根据我们的实验结果,在最佳位置 a=1.6cm 提取的建议模式向量达到了最高的灵敏度、特异性和准确性。此外,该技术利用较少的生理参数获得了 100%的正确分类率(CRC)。精度评估证实了与 DMR-IR 的乳房热图分类的其他技术相比,所提出的方法具有性能优势。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/06ae/8618047/878e10e84670/sensors-21-07751-g013.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/06ae/8618047/878e10e84670/sensors-21-07751-g013.jpg

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本文引用的文献

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Combining Genetic Algorithms and SVM for Breast Cancer Diagnosis Using Infrared Thermography.基于遗传算法和支持向量机的红外热成像乳腺癌诊断方法。
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