Xia Xiaoyan, Xiao Jiao
School of Traditional Chinese Medicine, Shanxi Datong University, Datong 037009, China.
Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang 110016, China.
Molecules. 2021 Nov 17;26(22):6934. doi: 10.3390/molecules26226934.
Type 2 diabetes mellitus (T2DM) is a noteworthy worldwide public health problem. It represents a complex metabolic disorder, mainly characterized as hyperglycemia and lipid dysfunction. The gut microbiota dysbiosis has been proposed to play a role in the development of diabetes. Recently, there has been considerable interest in the use of medicine food homology (MFH) and functional food herbs (FF) to ameliorate diabetes and lead to a natural and healthy life. Hence, this review compiles some reports and findings to demonstrate that the practical use of the MFH/FF can modulate the homoeostasis of gut microbiota, thereby ameliorating the development of T2DM. The results provided useful data to support further investigation of the functional basis and application of MFH/FF to treat T2DM through maintaining intestinal homeostasis.
2型糖尿病（T2DM）是一个值得关注的全球性公共卫生问题。它代表一种复杂的代谢紊乱，主要特征为高血糖和脂质功能障碍。肠道微生物群失调被认为在糖尿病的发展中起作用。最近，人们对使用药食同源（MFH）和功能性食用草药（FF）来改善糖尿病并实现自然健康的生活产生了浓厚兴趣。因此，本综述汇编了一些报告和研究结果，以证明MFH/FF的实际应用可以调节肠道微生物群的稳态，从而改善T2DM的发展。这些结果提供了有用的数据，以支持进一步研究MFH/FF通过维持肠道稳态治疗T2DM的功能基础和应用。
