Instituto de Magnetismo Aplicado, 'Salvador Velayos', UCM-CSIC-ADIF, Las Rozas, P.O. Box 155, 28230 Madrid, Spain.
Servicio de Dosimetría y Radioprotección, Hospital General Universitario Gregorio Marañón, 28007 Madrid, Spain.
Molecules. 2021 Nov 17;26(22):6943. doi: 10.3390/molecules26226943.
The Pechini method has been used as a synthetic route for obtaining self-assembling magnetic and plasmonic nanoparticles in hybrid silica nanostructures. This manuscript evaluates the influence of shaking conditions, reaction time, and pH on the size and morphology of the nanostructures produced. The characterization of the nanomaterials was carried out by transmission electron microscopy (TEM) to evaluate the coating and size of the nanomaterials, Fourier-transform infrared spectroscopy (FT-IR) transmission spectra to evaluate the presence of the different coatings, and thermogravimetric analysis (TGA) curves to determine the amount of coating. The results obtained show that the best conditions to obtain core-satellite nanostructures with homogeneous silica shells and controlled sizes (<200 nm) include the use of slightly alkaline media, the ultrasound activation of silica condensation, and reaction times of around 2 h. These findings represent an important framework to establish a new general approach for the click chemistry assembling of inorganic nanostructures.
皮钦尼法已被用作一种合成途径，用于在混合二氧化硅纳米结构中获得自组装磁性和等离子体纳米粒子。本文评估了振动条件、反应时间和 pH 值对所制备纳米结构的尺寸和形态的影响。通过透射电子显微镜（TEM）对纳米材料进行了表征，以评估纳米材料的涂层和尺寸，通过傅里叶变换红外光谱（FT-IR）透射光谱评估不同涂层的存在，通过热重分析（TGA）曲线确定涂层量。所得结果表明，获得具有均匀二氧化硅壳和受控尺寸（<200nm）的核-卫星纳米结构的最佳条件包括使用略碱性介质、超声激活二氧化硅缩合以及反应时间约 2 小时。这些发现为点击化学组装无机纳米结构提供了一个重要的框架，代表了一种新的通用方法。
